An Efficient Synthesis of Darunavir Substantially Free from Impurities: Synthesis and Characterization of Novel Impurities

Author:

Rapolu Rajesh Kumar12,Areveli Srinivas1,Raju V. V. N. K. V. Prasada1,Navuluri Srinivasu2,Chavali Murthy234,Mulakayala Naveen5ORCID

Affiliation:

1. Granules India Limited – R&D Center, Plot No.56 Road No.5, ALEAP Industrial Area, Pragathinagar Hyderabad 5000072 India

2. Department of ChemistryDepartment of Sciences and HumanitiesVignan's Foundation for Science, Technology and Research (VFSTR) Guntur 522 213 India

3. Shree Velagapudi Ramakrishna Memorial College (SVRMC; Autonomous) Nagaram 522 268 Guntur District, Andhra Pradesh INDIA

4. MCETRC, Tenali Guntur 522 201, Andhra Pradesh INDIA

5. SVAK Life sciencesALEAP Industrial area, Pragathinagar Hyderabad 500090 India

Publisher

Wiley

Subject

General Chemistry

Reference42 articles.

1. “Global HIV/AIDS Overview” by UNAIDS to be found under https://www.hiv.gov/federal-response/pepfar-global-aids/global-hiv-aids-overview 2017.

2. NIH Guidelines: http://aidsinfo.nih.gov/guidelines (retrieved 22 Sep 2016); WHO Guidelines: http://www.who.int/hiv/pub/arv/ arv2016/en/ (published June2016).

3.  

4.  “Darunavir”. The American Society of Health-System Pharmacists. Retrieved 28 November 2016. 

5. “Darunavir (Prezista) Use During Pregnancy”. www.drugs.com. Retrieved 4 December 2016 

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