New and Highly Efficient Column Chromatographic Extraction and Simple Purification of Camptothecin from Camptotheca acuminata and Nothapodytes pittosporoides

Author:

Zeng Xue-Hua1,Li Yue-Hong1,Wu Shan-Shan1,Hao Rui-Lin1,Li Hui1,Ni He1,Han Han-Bing12,Li Hai-Hang1

Affiliation:

1. Guangdong Provincial Key Laboratory of Biotechnology for Plant Development, College of Life Sciences; South China Normal University; Guangzhou China 510631

2. College of Chemistry and Life Sciences; Guangdong University of Petrochemical Technology; 139 Guandu Road 2 Maoming City Guangdong 525000 China

Funder

The Science and Technology Programs of Guangdong Province

Natural Science Funds of Guangdong Province

Publisher

Wiley

Subject

Complementary and alternative medicine,Drug Discovery,Plant Science,Molecular Medicine,General Medicine,Biochemistry,Food Science,Analytical Chemistry

Reference34 articles.

1. Camptothecin production by in vitro cultures and plant regeneration in Ophiorrhiza species;Asano;Methods Mol Biol,2009

2. Comparison of techniques for the extraction of the anti-cancer drug camptothecin from Nothapodytes foetida;Fulzele;J Chromatogr A,2005

3. Study on the separation of natural camptothecin and 10-hydroxycamptothecin by column chromatography;Guo;Acta Chin Med Pharmacol,2005

4. Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I;Hsiang;J Biol Chem,1985

5. Camptothecin accumulation and variations in camptotheca;Li;Planta Med,2002

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