1. Brigham and Women's Hospital, Division of Preventive Medicine; Harvard Medical School; 900 Commonwealth Avenue Boston MA 02118 U.S.A.
2. Department of Biostatistics; Boston University School of Public Health Harvard Clinical Research Institute; 801 Massachusetts Avenue Boston MA 02118 U.S.A.
3. Department of Mathematics and Statistics; Boston University; 111 Cummington Mall Boston MA 02215 U.S.A.