Cortical thickness across the lifespan: Data from 17,075 healthy individuals aged 3–90 years

Author:

Frangou Sophia12ORCID,Modabbernia Amirhossein1,Williams Steven C. R.3,Papachristou Efstathios4,Doucet Gaelle E.5,Agartz Ingrid678,Aghajani Moji910ORCID,Akudjedu Theophilus N.1112,Albajes‐Eizagirre Anton1314,Alnæs Dag615,Alpert Kathryn I.16,Andersson Micael17,Andreasen Nancy C.18,Andreassen Ole A.6,Asherson Philip19,Banaschewski Tobias20,Bargallo Nuria2122,Baumeister Sarah20,Baur‐Streubel Ramona23,Bertolino Alessandro24,Bonvino Aurora25,Boomsma Dorret I.25,Borgwardt Stefan26,Bourque Josiane27,Brandeis Daniel20,Breier Alan28,Brodaty Henry29,Brouwer Rachel M.30ORCID,Buitelaar Jan K.313233,Busatto Geraldo F.34,Buckner Randy L.3536,Calhoun Vincent37,Canales‐Rodríguez Erick J.1314,Cannon Dara M.12,Caseras Xavier38,Castellanos Francisco X.39,Cervenka Simon840,Chaim‐Avancini Tiffany M.34,Ching Christopher R. K.41ORCID,Chubar Victoria42,Clark Vincent P.4344,Conrod Patricia45,Conzelmann Annette46,Crespo‐Facorro Benedicto1447,Crivello Fabrice48,Crone Eveline A.4950,Dale Anders M.5152,Dannlowski Udo53,Davey Christopher54,Geus Eco J. C.25,Haan Lieuwe55,Zubicaray Greig I.56,Braber Anouk25,Dickie Erin W.5758,Di Giorgio Annabella59,Doan Nhat Trung6,Dørum Erlend S.66061,Ehrlich Stefan6263,Erk Susanne64,Espeseth Thomas5965,Fatouros‐Bergman Helena840,Fisher Simon E.3366ORCID,Fouche Jean‐Paul67,Franke Barbara336869,Frodl Thomas70ORCID,Fuentes‐Claramonte Paola1314,Glahn David C.71ORCID,Gotlib Ian H.72ORCID,Grabe Hans‐Jörgen7374,Grimm Oliver75ORCID,Groenewold Nynke A.6776,Grotegerd Dominik76,Gruber Oliver77,Gruner Patricia7879,Gur Rachel E.278081,Gur Ruben C.278081,Hahn Tim53,Harrison Ben J.82,Hartman Catharine A.83,Hatton Sean N.84ORCID,Heinz Andreas64,Heslenfeld Dirk J.85,Hibar Derrek P.86,Hickie Ian B.84,Ho Beng‐Choon18,Hoekstra Pieter J.87,Hohmann Sarah20,Holmes Avram J.88,Hoogman Martine3368ORCID,Hosten Norbert89,Howells Fleur M.6776,Hulshoff Pol Hilleke E.30ORCID,Huyser Chaim90,Jahanshad Neda42,James Anthony91,Jernigan Terry L.92,Jiang Jiyang29,Jönsson Erik G.6,Joska John A.67,Kahn Rene1,Kalnin Andrew93,Kanai Ryota94,Klein Marieke336895,Klyushnik Tatyana P.96,Koenders Laura55,Koops Sanne30,Krämer Bernd77ORCID,Kuntsi Jonna19,Lagopoulos Jim97,Lázaro Luisa1498,Lebedeva Irina96,Lee Won Hee1,Lesch Klaus‐Peter99,Lochner Christine100,Machielsen Marise W. J.55,Maingault Sophie48,Martin Nicholas G.101,Martínez‐Zalacaín Ignacio14102,Mataix‐Cols David840,Mazoyer Bernard48,McDonald Colm12,McDonald Brenna C.28,McIntosh Andrew M.103,McMahon Katie L.104,McPhilemy Genevieve12,Meinert Susanne53,Menchón José M.14102,Medland Sarah E.101,Meyer‐Lindenberg Andreas105,Naaijen Jilly3233,Najt Pablo12,Nakao Tomohiro106,Nordvik Jan E.107,Nyberg Lars17108,Oosterlaan Jaap109,Foz Víctor Ortiz‐García14110111,Paloyelis Yannis3,Pauli Paul23112,Pergola Giulio24,Pomarol‐Clotet Edith1314,Portella Maria J.13113,Potkin Steven G.114,Radua Joaquim822115,Reif Andreas75,Rinker Daniel A.6,Roffman Joshua L.36,Rosa Pedro G. P.34,Sacchet Matthew D.116,Sachdev Perminder S.29,Salvador Raymond13,Sánchez‐Juan Pascual110117,Sarró Salvador13,Satterthwaite Theodore D.27,Saykin Andrew J.28,Serpa Mauricio H.34,Schmaal Lianne118119,Schnell Knut120,Schumann Gunter19121,Sim Kang122,Smoller Jordan W.123,Sommer Iris124,Soriano‐Mas Carles14102,Stein Dan J.100,Strike Lachlan T.125,Swagerman Suzanne C.25,Tamnes Christian K.67126,Temmingh Henk S.67,Thomopoulos Sophia I.41,Tomyshev Alexander S.96,Tordesillas‐Gutiérrez Diana13127,Trollor Julian N.29,Turner Jessica A.128,Uhlmann Anne67,Heuvel Odile A.9,Meer Dennis615129,Wee Nic J. A.130131,Haren Neeltje E. M.132,Ent Dennis25,Erp Theo G. M.114133134,Veer Ilya M.64,Veltman Dick J.9,Voineskos Aristotle5758,Völzke Henry134135136,Walter Henrik64,Walton Esther137,Wang Lei138,Wang Yang139,Wassink Thomas H.18,Weber Bernd140,Wen Wei29,West John D.28,Westlye Lars T.60,Whalley Heather103,Wierenga Lara M.141,Wittfeld Katharina7374,Wolf Daniel H.27,Worker Amanda2,Wright Margaret J.125,Yang Kun142,Yoncheva Yulyia143,Zanetti Marcus V.34144,Ziegler Georg C.145,Thompson Paul M.41,Dima Danai3146ORCID,

Affiliation:

1. Department of Psychiatry Icahn School of Medicine at Mount Sinai New York City New York USA

2. Department of Psychiatry, Djavad Mowafaghian Centre for Brain Health University of British Columbia Vancouver Canada

3. Department of Neuroimaging Institute of Psychiatry, Psychology and Neuroscience, King's College London London United Kingdom

4. Psychology and Human Development Institute of Education, University College London London United Kingdom

5. Institute for Human Neuroscience Boys Town National Research Hospital Omaha Nebraska USA

6. Norwegian Centre for Mental Disorders Research (NORMENT) Institute of Clinical Medicine, University of Oslo Oslo Norway

7. Department of Psychiatric Research Diakonhjemmet Hospital Oslo Norway

8. Centre for Psychiatric Research, Department of Clinical Neuroscience Karolinska Institutet Solna Sweden

9. Department of Psychiatry Amsterdam University Medical Centre, Vrije Universiteit Amsterdam Netherlands

10. Section Forensic Family & Youth Care Institute of Education & Child Studies Leiden University Netherlands

11. Institute of Medical Imaging and Visualisation, Department of Medical Science and Public Health, Faculty of Health and Social Sciences Bournemouth University Poole United Kingdom

12. Clinical Neuroimaging Laboratory, Centre for Neuroimaging and Cognitive Genomics and NCBES Galway Neuroscience Centre National University of Ireland Galway Ireland

13. FIDMAG Germanes Hospitalàries Barcelona Spain

14. Mental Health Research Networking Center (CIBERSAM) Madrid Spain

15. Division of Mental Health and Addiction Institute of Clinical Medicine, University of Oslo Oslo Norway

16. Radiologics, Inc Saint Louis Missouri USA

17. Department of Integrative Medical Biology Umeå University Umeå Sweden

18. Department of Psychiatry, Carver College of Medicine The University of Iowa Iowa City Iowa USA

19. Social, Genetic and Developmental Psychiatry Centre Institute of Psychiatry, Psychology and Neuroscience, King's College London London United Kingdom

20. Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health Heidelberg University Heidelberg Germany

21. Imaging Diagnostic Centre Hospital Clinic, Barcelona University Clinic Barcelona Spain

22. August Pi i Sunyer Biomedical Research Institut (IDIBAPS) Barcelona Spain

23. Department of Psychology, Biological Psychology, Clinical Psychology and Psychotherapy University of Würzburg Würzburg Germany

24. Department of Basic Medical Science, Neuroscience and Sense Organs University of Bari Aldo Moro Bari Italy

25. Department of Biological Psychology Vrije Universiteit Amsterdam Netherlands

26. Department of Psychiatry & Psychotherapy University of Lübeck Lübeck Germany

27. Department of Psychiatry University of Pennsylvania Philadelphia Pennsylvania USA

28. Department of Radiology and Imaging Sciences Indiana University School of Medicine Indianapolis Indiana USA

29. Centre for Healthy Brain Ageing, School of Psychiatry University of New South Wales Kensington New South Wales Australia

30. Rudolf Magnus Institute of Neuroscience University Medical Center Utrecht Utrecht Netherlands

31. Donders Center of Medical Neurosciences Radboud University Nijmegen Netherlands

32. Donders Centre for Cognitive Neuroimaging Radboud University Nijmegen Netherlands

33. Donders Institute for Brain, Cognition and Behaviour Radboud University Nijmegen Netherlands

34. Laboratory of Psychiatric Neuroimaging, Departamento e Instituto de Psiquiatria, Hospital das Clinicas HCFMUSP, Faculdade de Medicina Universidade de São Paulo São Paulo Brazil

35. Department of Psychology, Center for Brain Science Harvard University Cambridge Massachusetts USA

36. Department of Psychiatry Massachusetts General Hospital Boston Massachusetts USA

37. Tri‐Institutional Center for Translational Research in Neuroimaging and Data Science (TReNDS), Georgia State University, Georgia Institute of Technology Emory University, USA Neurology, Radiology, Psychiatry and Biomedical Engineering, Emory University Atlanta Georgia USA

38. MRC Centre for Neuropsychiatric Genetics and Genomics Cardiff University Cardiff United Kingdom

39. Department of Child and Adolescent Psychiatry New York University New York New York USA

40. Stockholm Health Care Services Stockholm Sweden

41. Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine University of Southern California Marina del Rey California USA

42. Mind‐Body Research Group, Department of Neuroscience KU Leuven Leuven Belgium

43. Department of Psychology University of New Mexico Albuquerque New Mexico USA

44. Mind Research Network Albuquerque New Mexico USA

45. Department of Psychiatry Université de Montréal Montreal Canada

46. Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy University of Tübingen Tübingen Germany

47. HU Virgen del Rocio, IBiS University of Sevilla Sevilla Spain

48. Groupe d'Imagerie Neurofonctionnelle, Institut des Maladies Neurodégénératives, UMR5293 Université de Bordeaux Bordeaux France

49. Erasmus School of Social and Behavioural Sciences Erasmus University Rotterdam Rotterdam Netherlands

50. Faculteit der Sociale Wetenschappen, Instituut Psychologie Universiteit Leiden Leiden Netherlands

51. Center for Multimodal Imaging and Genetics, Department of Neuroscience University of California‐San Diego San Diego California USA

52. Department of Radiology University of California‐San Diego San Diego California USA

53. Department of Psychiatry and Psychotherapy University of Münster Germany

54. Department of Psychiatry University of Melbourne Melbourne Australia

55. Academisch Medisch Centrum Universiteit van Amsterdam Amsterdam Netherlands

56. Faculty of Health, Institute of Health and Biomedical Innovation Queensland University of Technology Queensland Australia

57. Kimel Family Translational Imaging Genetics Laboratory, Campbell Family Mental Health Research Institute CAMH Campbell Canada

58. Department of Psychiatry University of Toronto Toronto Canada

59. Biological Psychiatry Lab Fondazione IRCCS Casa Sollievo della Sofferenza San Giovanni Rotondo (FG) Italy

60. Department of Psychology University of Oslo Oslo Norway

61. Sunnaas Rehabilitation Hospital HT Nesodden Norway

62. Division of Psychological and Social Medicine and Developmental Neurosciences Technische Universität Dresden Dresden Germany

63. Faculty of Medicine Universitätsklinikum Carl Gustav Carus an der TU Dresden Dresden Germany

64. Division of Mind and Brain Research, Department of Psychiatry and Psychotherapy Charité‐Universitätsmedizin Berlin Berlin Germany

65. Bjørknes College Oslo Norway

66. Language and Genetics Department Max Planck Institute for Psycholinguistics Nijmegen Netherlands

67. Department of Psychiatry and Mental Health University of Cape Town Cape Town South Africa

68. Department of Human Genetics Radboud University Medical Center Nijmegen Netherlands

69. Department of Psychiatry Radboud University Medical Center Nijmegen Netherlands

70. Department of Psychiatry and Psychotherapy Otto von Guericke University Magdeburg Magdeburg Germany

71. Department of Psychiatry Tommy Fuss Center for Neuropsychiatric Disease Research Boston Children's Hospital, Harvard Medical School Boston Massachusetts USA

72. Department of Psychology Stanford University Stanford California USA

73. Department of Psychiatry and Psychotherapy University Medicine Greifswald, University of Greifswald Greifswald Germany

74. German Center for Neurodegenerative Diseases (DZNE) Site Rostock/Greifswald Greifswald Germany

75. Department for Psychiatry, Psychosomatics and Psychotherapy Universitätsklinikum Frankfurt, Goethe Universitat Frankfurt Germany

76. Neuroscience Institute University of Cape Town Cape Town South Africa

77. Section for Experimental Psychopathology and Neuroimaging, Department of General Psychiatry Heidelberg University Heidelberg Germany

78. Department of Psychiatry Yale University New Haven Connecticut USA

79. Learning Based Recovery Center VA Connecticut Health System West Haven Connecticut USA

80. Lifespan Brain Institute, Perelman School of Medicine University of Pennsylvania Philadelphia Pennsylvania USA

81. Children's Hospital of Philadelphia University of Pennsylvania Philadelphia Pennsylvania USA

82. Melbourne Neuropsychiatry Center University of Melbourne Melbourne Australia

83. Interdisciplinary Center Psychopathology and Emotion regulation University Medical Center Groningen, University of Groningen Groningen Netherlands

84. Brain and Mind Centre University of Sydney Sydney Australia

85. Departments of Experimental and Clinical Psychology Vrije Universiteit Amsterdam Amsterdam Netherlands

86. Personalized Healthcare, Genentech, Inc. South San Francisco California USA

87. Department of Psychiatry University Medical Center Groningen, University of Groningen Groningen Netherlands

88. Department of Psychology Yale University New Haven Connecticut USA

89. Norbert Institute of Diagnostic Radiology and Neuroradiology University Medicine Greifswald, University of Greifswald Greifswald Germany

90. De Bascule, Academic Centre for Children and Adolescent Psychiatry Amsterdam Netherlands

91. Department of Psychiatry Oxford University Oxford United Kingdom

92. Center for Human Development, Departments of Cognitive Science, Psychiatry, and Radiology University of California San Diego California USA

93. Department of Radiology Ohio State University College of Medicine Columbus Ohio USA

94. Department of Neuroinformatics Araya, Inc. Tokyo Japan

95. Department of Psychiatry University of California San Diego San Diego California USA

96. Mental Health Research Center Russian Academy of Medical Sciences Moscow Russia

97. Sunshine Coast Mind and Neuroscience Thompson Institute, University of the Sunshine Coast Queensland Australia

98. Department of Child and Adolescent Psychiatry and Psychology Hospital Clinic, University of Barcelona Barcelona Spain

99. Department of Psychiatry, Psychosomatics and Psychotherapy Julius‐Maximilians Universität Würzburg Würzburg Germany

100. SA MRC Unit on Risk and Resilience in Mental Disorders, Department of Psychiatry Stellenbosch University Stellenbosch South Africa

101. Queensland Institute of Medical Research Berghofer Medical Research Institute Queensland Australia

102. Department of Psychiatry Bellvitge University Hospital‐IDIBELL, University of Barcelona Barcelona Spain

103. Division of Psychiatry University of Edinburgh Edinburgh United Kingdom

104. School of Clinical Sciences, Institute of Health and Biomedical Innovation Queensland University of Technology Queensland Australia

105. Department of Psychiatry and Psychotherapy Central Institute of Mental Health, Heidelberg University Heidelberg Germany

106. Department of Clinical Medicine Kyushu University Fukuoka Japan

107. CatoSenteret Rehabilitation Hospital Son Norway

108. Department of Radiation Sciences Umeå Center for Functional Brain Imaging, Umeå University Umeå Sweden

109. Department of Clinical Neuropsychology Amsterdam University Medical Centre, Vrije Universiteit Amsterdam Amsterdam Netherlands

110. Department of Psychiatry University Hospital “Marques de Valdecilla”, Instituto de Investigación Valdecilla (IDIVAL) Santander Spain

111. Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM) Instituto de Salud Carlos III Madrid Spain

112. Centre of Mental Health University of Würzburg Würzburg Germany

113. Department of Psychiatry Hospital de la Santa Creu i Sant Pau, Institut d'Investigació Biomèdica Sant Pau, Universitat Autònoma de Barcelona Barcelona Spain

114. Department of Psychiatry University of California at Irvine Irvine California USA

115. Department of Psychosis Studies Institute of Psychiatry, Psychology & Neuroscience, King's College London London United Kingdom

116. Center for Depression, Anxiety, and Stress Research McLean Hospital, Harvard Medical School Boston Massachusetts USA

117. Centro de Investigacion Biomedica en Red en Enfermedades Neurodegenerativas (CIBERNED) Valderrebollo Spain

118. Orygen The National Centre of Excellence in Youth Mental Health Melbourne Australia

119. Centre for Youth Mental Health The University of Melbourne Melbourne Australia

120. Department of Psychiatry and Psychotherapy University Medical Center Göttingen Göttingen Germany

121. Centre for Population Neuroscience and Precision Medicine Institute of Psychiatry, Psychology & Neuroscience, King's College London London United Kingdom

122. Department of General Psychiatry Institute of Mental Health Singapore Singapore

123. Center for Genomic Medicine Massachusetts General Hospital Boston Massachusetts USA

124. Department of Biomedical Sciences of Cells and Systems, Rijksuniversiteit Groningen University Medical Center Groningen Groningen Netherlands

125. Queensland Brain Institute University of Queensland Queensland Australia

126. PROMENTA Research Center, Department of Psychology University of Oslo Oslo Norway

127. Neuroimaging Unit, Technological Facilities Valdecilla Biomedical Research Institute IDIVAL Cantabria Spain

128. College of Arts and Sciences Georgia State University Atlanta Georgia USA

129. School of Mental Health and Neuroscience, Faculty of Health, Medicine and Life Sciences Maastricht University Maastricht Netherlands

130. Department of Psychiatry Leiden University Medical Center Leiden Netherlands

131. Leiden Institute for Brain and Cognition Leiden University Medical Center Leiden Netherlands

132. Department of Child and Adolescent Psychiatry/Psychology Erasmus University Medical Center, Sophia Children's Hospital Rotterdam The Netherlands

133. Center for the Neurobiology of Learning and Memory University of California Irvine Irvine California USA

134. Institute of Community Medicine University Medicine, Greifswald, University of Greifswald Greifswald Germany

135. German Centre for Cardiovascular Research (DZHK), partner site Greifswald Greifswald Germany

136. German Center for Diabetes Research (DZD), partner site Greifswald Greifswald Germany

137. Department of Psychology University of Bath Bath United Kingdom

138. Department of Psychiatry and Behavioral Sciences, Feinberg School of Medicine Northwestern University Evanston Illinois USA

139. Department of Radiology Medical College of Wisconsin Milwaukee Wisconsin USA

140. Institute for Experimental Epileptology and Cognition Research University of Bonn Bonn Germany

141. Developmental and Educational Psychology Unit, Institute of Psychology Leiden University Leiden Netherlands

142. National High Magnetic Field Laboratory Florida State University Tallahassee Florida USA

143. Department of Child and Adolescent Psychiatry, Child Study Center NYU Langone Health New York City New York USA

144. Instituto de Ensino e Pesquisa Hospital Sírio‐Libanês São Paulo Brazil

145. Division of Molecular Psychiatry, Center of Mental Health University of Würzburg Würzburg Germany

146. Department of Psychology, School of Arts and Social Sciences City University of London London United Kingdom

Funder

National Center for Research Resources

ZonMw

National Institute of Mental Health

FP7 Ideas: European Research Council

Nederlandse Organisatie voor Wetenschappelijk Onderzoek

Medical Research Council Canada

Instituto de Salud Carlos III

Vetenskapsrådet

Icahn School of Medicine at Mount Sinai

Seventh Framework Programme

National Institutes of Health

South London and Maudsley NHS Foundation Trust

Publisher

Wiley

Subject

Neurology (clinical),Neurology,Radiology, Nuclear Medicine and imaging,Radiological and Ultrasound Technology,Anatomy

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