Using a rhabdomyosarcoma patient-derived xenograft to examine precision medicine approaches and model acquired resistance

Author:

Monsma David J.1,Cherba David M.1,Richardson Patrick J.1,Vance Sean1ORCID,Rangarajan Sanjeet1ORCID,Dylewski Dawna1,Eugster Emily1,Scott Stephanie B.1,Beuschel Nicole L.1,Davidson Paula J.1,Axtell Richard2,Mitchell Deanna2,Lester Eric P.3,Junewick Joseph J.4,Webb Craig P.5,Monks Noel R.1ORCID

Affiliation:

1. Van Andel Research Institute; Center for Translational Medicine; Grand Rapids Michigan

2. Helen DeVos Childrens Hospital; Pediatric Hematology/Oncology; Grand Rapids Michigan

3. Oncology Care Associates PLLC; Saint Joseph Michigan

4. Helen DeVos Children's Hospital, Advanced Radiology Services; Michigan State University; Grand Rapids Michigan

5. NuMedii, Inc.; Palo Alto California

Publisher

Wiley

Subject

Oncology,Hematology,Pediatrics, Perinatology and Child Health

Reference56 articles.

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3. Gastrointestinal stromal tumors (GIST): A rare entity, a tumor model for personalized therapy, and yet ten different molecular subtypes;Blay;Discov Med,2012

4. Gene expression classification of colon cancer into molecular subtypes: Characterization, validation, and prognostic value;Marisa;PLoS Med,2013

5. Exploiting the cancer genome: Strategies for the discovery and clinical development of targeted molecular therapeutics;Yap;Annu Rev Pharmacol Toxicol,2012

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