Mathematical analysis of the dynamics of a fractional‐order tuberculosis epidemic in a patchy environment under the influence of re‐infection

Author:

Jabbari A.1ORCID,Lotfi M.2,Kheiri H.3ORCID,Khajanchi S.4

Affiliation:

1. Marand Faculty of Engineering University of Tabriz Tabriz Iran

2. Institute of Bioinformatics University Medicine Greifswald Greifswald Germany

3. Department of Applied Mathematics, Faculty of Mathematical Sciences University of Tabriz Tabriz Iran

4. Department of Mathematics Presidency University Kolkata India

Abstract

In human societies, memory has a significant impact on the procedure of progression and control of epidemics. Therefore, fractional differential equations govern an epidemic model, including the memory effect. Since infectious diseases can spread from one place to another, human movement impacts the prevalence of such diseases. In this study, we present a two‐patch model for tuberculosis with fractional order and exogenous re‐infection, in which susceptible individuals can move without any obstacle between the patches. The present work establishes the effect of population movement and the backward bifurcation phenomenon on the prevalence of the tuberculosis epidemic with fractional‐order derivatives. Furthermore, to show that the proposed model has backward bifurcation, we provide some conditions between the model's parameters, so in this case, the model of tuberculosis has numerous boundary points. We show the tuberculosis model can exhibit backward bifurcation neither in case of exogenous re‐infection, with some conditions, nor in the situation that the model is vacant from any re‐infection. In contrast, the disease‐free equilibrium of the model is globally asymptotically stable when . Furthermore, we investigate the fractional‐order derivative on the spread of infection. The results show that can perform the function of adventure or expertise of people about the disease background.

Publisher

Wiley

Subject

General Engineering,General Mathematics

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4. World Health Organization Guidelines on the management of latent TB infection 2015. Available from:http://apps.who.int/medicinedocs/documents/s21682en/s21682en.pdf

5. Quantifying the Intrinsic Transmission Dynamics of Tuberculosis

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