Evaluation of ChatGPT's performance in providing treatment recommendations for pediatric diseases

Author:

Wei Qiuhong12ORCID,Wang Yanqin3,Yao Zhengxiong4,Cui Ying5,Wei Bo6,Li Tingyu1,Xu Ximing7

Affiliation:

1. Children Nutrition Research Center Children's Hospital of Chongqing Medical University National Clinical Research Center for Child Health and Disorders Ministry of Education Key Laboratory of Child Development and Disorders China International Science and Technology Cooperation Base of Child Development and Critical Disorders Chongqing Key Laboratory of Childhood Nutrition and Health Chongqing China

2. College of Medical Informatics Medical Data Science Academy Chongqing Engineering Research Center for Clinical Big‐Data and Drug Evaluation Chongqing Medical University Chongqing China

3. Department of Nephrology Children's Hospital of Chongqing Medical University Chongqing China

4. Department of Neurology Children's Hospital of Chongqing Medical University Chongqing China

5. Department of Biomedical Data Science Stanford University School of Medicine Stanford California USA

6. Department of Global Statistics and Data Science BeiGene USA Inc. San Mateo California USA

7. Big Data Center for Children's Medical Care Children's Hospital of Chongqing Medical University Chongqing China

Abstract

AbstractWith the advance of artificial intelligence technology, large language models such as ChatGPT are drawing substantial interest in the healthcare field. A growing body of research has evaluated ChatGPT's performance in various medical departments, yet its potential in pediatrics remains under‐studied. In this study, we presented ChatGPT with a total of 4160 clinical consultation questions in both English and Chinese, covering 104 pediatric conditions, and repeated each question independently 10 times to assess the accuracy of its responses in pediatric disease treatment recommendations. ChatGPT achieved an overall accuracy of 82.2% (95% CI: 81.0%–83.4%), with superior performance in addressing common diseases (84.4%, 95% CI: 83.2%–85.7%), offering general treatment advice (83.5%, 95% CI: 81.9%–85.1%), and responding in English (93.0%, 95% CI: 91.9%–94.1%). However, it was prone to errors in disease definitions, medications, and surgical treatment. In conclusion, while ChatGPT shows promise in pediatric treatment recommendations with notable accuracy, cautious optimism is warranted regarding the potential application of large language models in enhancing patient care.

Publisher

Wiley

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