Germline mutations in penetrant cancer predisposition genes are rare in men with prostate cancer selecting active surveillance

Author:

Brady Lauren1,Newcomb Lisa F.23,Zhu Kehao2,Zheng Yingye2,Boyer Hilary23,Sarkar Navonil De1,McKenney Jesse K.4,Brooks James D.5,Carroll Peter R.6,Dash Atreya7,Ellis William J.3,Filson Christopher P.89,Gleave Martin E.10,Liss Michael A.11,Martin Frances12,Morgan Todd M.13,Thompson Ian M.14,Wagner Andrew A.15,Pritchard Colin C.16,Lin Daniel W.23,Nelson Peter S.13ORCID

Affiliation:

1. Division of Human Biology Fred Hutchinson Cancer Center Seattle Washington USA

2. Division of Public Health Sciences Fred Hutchinson Cancer Center Seattle Washington USA

3. Department of Urology University of Washington Seattle Washington USA

4. Robert J. Tomsich Pathology and Laboratory Medicine Institute Cleveland Clinic Cleveland Ohio USA

5. Department of Urology Stanford University Stanford California USA

6. Department of Urology University of California San Francisco California USA

7. VA Puget Sound Health Care Systems Seattle WA USA

8. Department of Urology Emory University School of Medicine Atlanta Georgia USA

9. Winship Cancer Institute Emory Healthcare Atlanta Georgia USA

10. Department of Urologic Sciences University of British Columbia Vancouver British Columbia Canada

11. Department of Urology University of Texas Health Sciences Center San Antonio Texas USA

12. Department of Urology Eastern Virginia Medical School Virginia Beach Virginia USA

13. Department of Urology University of Michigan Ann Arbor Michigan USA

14. CHRISTUS Medical Center Hospital San Antonio Texas USA

15. Division of Urology Beth Israel Deaconess Medical Center Boston Massachusetts USA

16. Department of Laboratory Medicine and Pathology University of Washington Seattle WA USA

Funder

Canary Foundation

Congressionally Directed Medical Research Programs

National Cancer Institute

Prostate Cancer Foundation

Publisher

Wiley

Subject

Cancer Research,Radiology, Nuclear Medicine and imaging,Oncology

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