A case of eosinophilic pneumonia induced by lettuce

Author:

Sekiya Reina1,Nagano Tatsuya1ORCID,Moriyama Tatsuya2,Kawaguchi Aki1,Fukui Takafumi1,Mimura Chihiro1,Kimura Yohei3,Ohnishi Hisashi4,Kotani Yoshikazu3,Nishimura Yoshihiro1

Affiliation:

1. Division of Respiratory Medicine, Department of Internal Medicine Kobe University Graduate School of Medicine Kobe Japan

2. Department of Applied Biological Chemistry, Graduate School of Agriculture Kinki University Nara Japan

3. Department of Respiratory Medicine Hyogo Prefectural Awaji Medical Center Sumoto Japan

4. Department of Respiratory Medicine Akashi Medical Center Akashi Japan

Abstract

AbstractA 56‐year‐old female lettuce farmer was admitted to the hospital with a low‐grade fever, worsening cough, and dyspnoea. A blood test revealed eosinophilia and a high serum IgE concentration. The 3‐year follow‐up showed that her total IgE level increased in December, peaked in May, and suddenly decreased in August. This result was consistent with the lettuce harvest season. A chest x‐ray taken on admission showed an infiltrative shadow in the upper lung field. Chest CT revealed patchy ground glass opacity on the upper lung field and thickening of the bronchial wall. The bronchoalveolar lavage fluid contained 8% eosinophils. She was treated with prednisolone, and her symptoms and radiological findings improved. The 37 kDa protein that reacted with the patient's sera was identified by immunoblot analysis.

Publisher

Wiley

Subject

Pulmonary and Respiratory Medicine

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