Chiral Inhibition of Rivaroxaban Derivatives Towards UDP-Glucuronosyltransferase (UGT) Isoforms

Author:

Yao Zhuhua1,Liu Yong-Zhe2,Ma Ai-Lun3,Wang Shu-Fen2,Lu Dan4,Hu Cui-Min5,Zhang Yan-Yan6,Wang Haina7,Hu Lingyun8,Deng Jun39,Yang Kun2,Fang Zhong-Ze2

Affiliation:

1. Department of Cardiology; Tianjin Union Medicine Centre; 300121 Tianjin People's Republic of China

2. Department of Toxicology, School of Public Health; Tianjin Medical University; Tianjin People's Republic of China

3. School of Pharmaceutical Science and Technology, Key Laboratory for Modern Drug Delivery & High-Efficiency; Tianjin University; Tianjin People's Republic of China

4. Department of Immunology, Tianjin Key Laboratory of Cellular and Molecular Immunology; Tianjin Medical University; Tianjin People's Republic of China

5. Tianjin Life Science Research Center, Department of Microbiology, School of Basic Medical Sciences; Tianjin Medical University; Tianjin People's Republic of China

6. Joint Center for Translational Medicine, Dalian Institute of Chemical Physics; Chinese Academy of Sciences and First Affiliated Hospital of Liaoning Medical University; Dalian People's Republic of China

7. College of Pharmaceutical Sciences; Shandong University; Jinan People's Republic of China

8. Shandong Cancer Hospital and Institute; Shandong People's Republic of China

9. Collaborative Innovation Center of Chemical Science and Engineering; Tianjin University; Tianjin People's Republic of China

Publisher

Wiley

Subject

Organic Chemistry,Spectroscopy,Drug Discovery,Pharmacology,Catalysis,Analytical Chemistry

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