Drug-Induced Convulsions in Nonclinical Safety Studies: Implication for Clinical Development
Author:
Affiliation:
1. Department of Regulatory Toxicology & Safety Assessment; H. Lundbeck A/S; Valby; Copenhagen; Denmark
Publisher
Wiley
Subject
Drug Discovery
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/ddr.21061/fullpdf
Reference38 articles.
1. Video-electroencephalography in conscious non human primate using radiotelemetry and computerized analysis: refinement of a safety pharmacology model;Authier;J Pharmacol Toxicol Methods,2009
2. Double bouquet cell in the human cerebral cortex and a comparison with other mammals;Ballesteros Yáñez;J Comp Neurol,2005
3. Striking differences in proconvulsant-induced alterations of seizure threshold in two rat models;Bankstahl;Neurotoxicology,2012
4. Measurement of cortical and hippocampal epileptiform activity in freely moving rats by means of implantable radiotelemetry;Bastlund;J Neurosci Methods,2004
5. Glossary of descriptive terminology for ictal semiology: report of the ILAE task force on classification and terminology;Blume;Epilepsia,2001
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