Asymmetric Amination of α-Chiral Aliphatic Aldehydes via Dynamic Kinetic Resolution to Access Stereocomplementary Brivaracetam and Pregabalin Precursors-Reference-Cited by-同舟云学术

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Asymmetric Amination of α-Chiral Aliphatic Aldehydes via Dynamic Kinetic Resolution to Access Stereocomplementary Brivaracetam and Pregabalin Precursors

Published:2017-12-21 Issue:4 Volume:360 Page:768-778
ISSN:1615-4150
Container-title:Advanced Synthesis & Catalysis
language:en
Short-container-title:Adv. Synth. Catal.

Author:

Fuchs Christine S.¹,Farnberger Judith E.¹,Steinkellner Georg¹²,Sattler Johann H.³,Pickl Mathias³,Simon Robert C.³,Zepeck Ferdinand⁴,Gruber Karl²,Kroutil Wolfgang³

Affiliation:

1. Austrian Centre of Industrial Biotechnology, ACIB GmbH, c/o; University of Graz; Harrachgasse 21 8010 Graz Austria

2. Institute of Molecular Biosciences; University of Graz; Humboldtstrasse 50/3 8010 Graz Austria

3. Institute of Chemistry, Organic and Bioorganic Chemistry; University of Graz; Harrachgasse 21 8010 Graz Austria

4. Sandoz GmbH; Biocatalysis Lab; Biochemiestrasse 10 6250 Kundl Austria

Publisher

Wiley

Subject

General Chemistry

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/adsc.201701449/fullpdf

Reference77 articles.

1. Brivaracetam: a rational drug discovery success story

2. From Basic Science to Blockbuster Drug: The Discovery of Lyrica

3. New developments in the management of partial-onset epilepsy: role of brivaracetam

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