Phase 1 study of the iodine absorption, safety, and tolerability of a 0.5% povidone‐iodine nasal spray (Nasodine)-Reference-Cited by-同舟云学术

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Phase 1 study of the iodine absorption, safety, and tolerability of a 0.5% povidone‐iodine nasal spray (Nasodine)

Published:2024-06-13 Issue:9 Volume:14 Page:1525-1528
ISSN:2042-6976
Container-title:International Forum of Allergy & Rhinology
language:en
Short-container-title:Int Forum Allergy Rhinol

Author:

Friedland Peter L.¹²^ORCID,Polasek Thomas M.³⁴,Topliss Duncan⁵⁶

Affiliation:

1. Medical School University of Western Australia Perth Western Australia Australia

2. Department Otolaryngology‐Head and Neck Surgery Sir Charles Gairdner Hospital Perth Western Australia Australia

3. Centre for Medicine Use and Safety Monash University Melbourne Victoria Australia

4. CMAX Clinical Research Adelaide South Australia Australia

5. Department of Endocrinology and Diabetes The Alfred Hospital Melbourne Victoria Australia

6. Department of Medicine Monash University Melbourne Victoria Australia

Abstract

Key points

PVP‐I is a widely used antiseptic but only recently proposed for intranasal use.

The extent of iodine absorption from available PVP‐I nasal products is unknown.

Iodine absorption from use of Nasodine (0.5% PVP‐I nasal spray) is not clinically significant.

Publisher

Wiley

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/alr.23389

Reference10 articles.

1. WHO.WHO model list of essential medicines—22nd list 2021.WHO;2021.

2. Topical iodophor preparations: Chemistry, microbiology, and clinical utility

3. Topical Povidone-Iodine as an Adjunctive Treatment for Recalcitrant Chronic Rhinosinusitis

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