Strategic white matter hyperintensity locations for cognitive impairment: A multicenter lesion‐symptom mapping study in 3525 memory clinic patients

Author:

Coenen Mirthe1ORCID,Kuijf Hugo J.2,Huenges Wajer Irene M. C.13,Duering Marco45,Wolters Frank J.678,Fletcher Evan F.9,Maillard Pauline M.9,Barkhof Frederik1011,Barnes Josephine12,Benke Thomas13,Boomsma Jooske M. F.14,Chen Christopher P. L. H.1516,Dal‐Bianco Peter17,Dewenter Anna4,Enzinger Christian1819,Ewers Michael4,Exalto Lieza G.12,Franzmeier Nicolai4,Groeneveld Onno120,Hilal Saima151621,Hofer Edith2223,Koek Dineke L.24,Maier Andrea B.1625,McCreary Cheryl R.26,Padilla Catarina S.1,Papma Janne M.827,Paterson Ross W.12,Pijnenburg Yolande A. L.14,Rubinski Anna4,Schmidt Reinhold22,Schott Jonathan M.12,Slattery Catherine F.12,Smith Eric E.26,Steketee Rebecca M. E.68,Sudre Carole H.28,van den Berg Esther827,van der Flier Wiesje M.14,Venketasubramanian Narayanaswamy1629,Vernooij Meike W.678,Xin Xu1516,DeCarli Charles9,Biessels Geert Jan1,Biesbroek J. Matthijs130,

Affiliation:

1. Department of Neurology and Neurosurgery UMC Utrecht Brain Center Utrecht The Netherlands

2. Image Sciences Institute University Medical Center Utrecht Utrecht The Netherlands

3. Experimental Psychology Helmholtz Institute Utrecht University Utrecht The Netherlands

4. Institute for Stroke and Dementia Research (ISD) University Hospital LMU Munich Munich Germany

5. Medical Image Analysis Center (MIAC) and Department of Biomedical Engineering University of Basel Basel Switzerland

6. Department of Radiology & Nuclear Medicine Erasmus MC University Medical Center Rotterdam The Netherlands

7. Department of Epidemiology Erasmus MC University Medical Center Rotterdam The Netherlands

8. Alzheimer Center Erasmus MC Erasmus MC University Medical Center Rotterdam The Netherlands

9. Department of Neurology University of California at Davis Davis California USA

10. Radiology & Nuclear Medicine Amsterdam UMC location Vrije Universiteit Amsterdam The Netherlands

11. UCL Institute of Neurology London UK

12. Dementia Research Centre UCL Queen Square Institute of Neurology UCL London UK

13. Clinic of Neurology Medical University Innsbruck Innsbruck Austria

14. Alzheimer Center Amsterdam Department of Neurology Amsterdam Neuroscience Vrije Universiteit Amsterdam Amsterdam UMC Amsterdam The Netherlands

15. Department of Pharmacology National University of Singapore Singapore Singapore

16. Memory, Aging and Cognition Center National University Health System Singapore Singapore

17. Department of Neurology Medical University Vienna Vienna Austria

18. Division of General Neurology Department of Neurology Medical University Graz Graz Austria

19. Division of Neuroradiology Interventional and Vascular Radiology Department of Radiology Medical University of Graz Graz Austria

20. Department of Neurology Isala MS Centre Isala Hospital Meppel The Netherlands

21. Saw Swee Hock School of Public Health National University of Singapore and National University Health System Singapore Singapore

22. Division of Neurogeriatrics, Department of Neurology Medical University of Graz Graz Austria

23. Institute for Medical Informatics Statistics and Documentation Medical University of Graz Graz Austria

24. Department of Geriatric Medicine University Medical Center Utrecht Utrecht The Netherlands

25. Department of Medicine National University of Singapore Singapore Singapore

26. Department of Clinical Neurosciences and Radiology and Hotchkiss Brain Institute University of Calgary Calgary Alberta Canada

27. Department of Neurology Erasmus MC University Medical Center Rotterdam The Netherlands

28. MRC Unit for Lifelong Health and Ageing the Centre for Medical Image Computing UCL London UK

29. Raffles Neuroscience Center Raffles Hospital Singapore Singapore

30. Department of Neurology Diakonessenhuis Hospital Utrecht The Netherlands

Publisher

Wiley

Subject

Psychiatry and Mental health,Cellular and Molecular Neuroscience,Geriatrics and Gerontology,Neurology (clinical),Developmental Neuroscience,Health Policy,Epidemiology

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