Normothermic Machine Perfusion (NMP) Inhibits Proinflammatory Responses in the Liver and Promotes Regeneration

Author:

Jassem Wayel12,Xystrakis Emmanuel1,Ghnewa Yasmeen G.1,Yuksel Muhammed1,Pop Oltin1,Martinez-Llordella Marc1,Jabri Yamen1,Huang Xiaohong1,Lozano Juan J.3,Quaglia Alberto1,Sanchez-Fueyo Alberto1,Coussios Constantin C.4,Rela Mohamed12,Friend Peter5,Heaton Nigel12,Ma Yun1

Affiliation:

1. Institute of Liver Studies, Department of Inflammation Biology; School of Immunology and Microbial Science, King’s College London; London United Kingdom

2. Transplantation Service; King’s College Hospital; London United Kingdom

3. Bioinformatics Platform; Biomedical Research Networking Center in Hepatic and Digestive Diseases; Barcelona Spain

4. Institute of Biomedical Engineering; University of Oxford; Oxford United Kingdom

5. Nuffield Department of Surgical Sciences; University of Oxford; Oxford United Kingdom

Funder

King’s Health Partners Research and Development Challenge Fund

Surgical Funds, King’s College Hospital Charity

NHS Blood and Transplant

Publisher

Wiley

Subject

Hepatology

Reference37 articles.

1. National Health Service (NHS) blood and transplant. 2017. Annual Report on Liver Transplantation https://nhsbtdbe.blob.core.windows.net/umbraco-assets-corp/5007/annual_liver_transplantation_report_2017.pdf

2. Single-center experience with liver transplantation from controlled non-heartbeating donors: a viable source of grafts;Muiesan;Ann Surg,2005

3. Developing a donation after cardiac death risk index for adult and pediatric liver transplantation;Elizabeth Khorsandi;World J Transpl,2017

4. The impact of ischemia/reperfusion injury on liver allografts from deceased after cardiac death versus deceased after brain death donors;Xu;PLoS ONE,2016

5. Effect of ischemic preconditioning on the genomic response to reperfusion injury in deceased donor liver transplantation;Jassem;Liver Transplant,2009

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