Tumor necrosis factor‐α‐mediated hepatocyte apoptosis stimulates fibrosis in the steatotic liver in mice
Author:
Affiliation:
1. Department of HepatologyTokyo Metropolitan Cancer and Infectious Diseases Center Komagome HospitalTokyo Japan
2. The Research Center for Hepatitis and ImmunologyNational Center for Global Health and MedicineChiba Japan
Funder
Takeda Science Foundation
Japan Agency for Medical Research and Development
Publisher
Wiley
Subject
Hepatology
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/hep4.1158
Reference50 articles.
1. Nonalcoholic Fatty Liver Disease
2. Liver Fibrosis, but No Other Histologic Features, Is Associated With Long-term Outcomes of Patients With Nonalcoholic Fatty Liver Disease
3. Apoptosis: The nexus of liver injury and fibrosis
4. Hepatocyte-specific disruption of Bcl-xL leads to continuous hepatocyte apoptosis and liver fibrotic responses
5. Hepatocyte apoptosis and fas expression are prominent features of human nonalcoholic steatohepatitis
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