Harnessing Artificial Intelligence to Optimize Long‐Term Maintenance Dosing for Antiretroviral‐Naive Adults with HIV‐1 Infection-Reference-Cited by-同舟云学术

Harnessing Artificial Intelligence to Optimize Long‐Term Maintenance Dosing for Antiretroviral‐Naive Adults with HIV‐1 Infection

Published:2019-11-11 Issue:4 Volume:3 Page:1900114
ISSN:2366-3987
Container-title:Advanced Therapeutics
language:en
Short-container-title:Adv. Therap.

Author:

Shen Yinzhong¹^ORCID,Liu Tingyi²³^ORCID,Chen Jun¹,Li Xin⁴,Liu Li¹,Shen Jiayin¹,Wang Jiangrong¹,Zhang Renfang¹,Sun Meiyan¹,Wang Zhenyan¹,Song Wei¹,Qi Tangkai¹,Tang Yang¹,Meng Xianmin⁵,Zhang Lijun⁶,Ho Dean⁷⁸⁹,Ho Chih‐Ming¹⁰,Ding Xianting⁴,Lu Hong‐Zhou¹

Affiliation:

1. Department of Infection and ImmunityShanghai Public Health Clinical CenterFudan University Shanghai 201508 China

2. Department of Mechanical and Industrial EngineeringUniversity of Massachusetts Amherst MA 01003 USA

3. Department of Mechanical and Industrial EngineeringInstitute for Applied Life Sciences (IALS)University of Massachusetts Amherst Amherst MA 01003 USA

4. Institute for Personalized MedicineState Key Laboratory of Oncogenes and Related GenesSchool of Biomedical EngineeringShanghai Jiao Tong University Shanghai 200030 China

5. Department of PharmacyShanghai Public Health Clinical CenterFudan University Shanghai 201508 China

6. Department of Scientific ResearchShanghai Public Health Clinical CenterFudan University Shanghai 201508 China

7. The N.1 Institute for Health (N.1)National University of Singapore Singapore 117456

8. Department of Biomedical Engineering, NUS EngineeringNational University of Singapore Singapore 117583

9. Department of PharmacologyYong Loo Lin School of MedicineNational University of Singapore Singapore 117600

10. Mechanical and Aerospace Engineering DepartmentBioengineering DepartmentUniversity of California California LA 90095 USA

Funder

Ministry of Science and Technology of the People's Republic of China

Bill and Melinda Gates Foundation

Publisher

Wiley

Subject

Pharmacology (medical),Biochemistry, medical,Genetics(clinical),Pharmaceutical Science,Pharmacology,Medicine (miscellaneous)

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/adtp.201900114

Reference52 articles.

1. Efficacy of 400 mg efavirenz versus standard 600 mg dose in HIV-infected, antiretroviral-naive adults (ENCORE1): a randomised, double-blind, placebo-controlled, non-inferiority trial

2. Efficacy and safety of efavirenz 400 mg daily versus 600 mg daily: 96-week data from the randomised, double-blind, placebo-controlled, non-inferiority ENCORE1 study

3. A reduced dose of darunavir/ritonavir is effective in PI-experienced HIV-infected patients

4. Toxicity Associated with Stavudine Dose Reduction from 40 to 30 mg in First-Line Antiretroviral Therapy

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