The Importance of Detail: How Differences in Ligand Structures Determine Distinct Functional Responses in Integrin α v β 3-Reference-Cited by-同舟云学术

The Importance of Detail: How Differences in Ligand Structures Determine Distinct Functional Responses in Integrin α v β 3

Published:2019-03-28 Issue:23 Volume:25 Page:5959-5970
ISSN:0947-6539
Container-title:Chemistry – A European Journal
language:en
Short-container-title:Chem. Eur. J.

Author:

Paladino Antonella¹,Civera Monica²,Curnis Flavio³,Paolillo Mayra⁴,Gennari Cesare²,Piarulli Umberto⁵,Corti Angelo³,Belvisi Laura²,Colombo Giorgio⁶^ORCID

Affiliation:

1. Istituto di Chimica del Riconoscimento Molecolare CNR via Mario Bianco 9 20131 Milan Italy

2. Dipartimento di ChimicaUniversità degli Studi di Milano via Golgi 19 20133 Milan Italy

3. IRCCS Ospedale San Raffaele Via Olgettina 60 20132 Milan Italy

4. Dipartimento di Scienze del FarmacoUniversità degli Studi di Pavia Viale Taramelli 6 27100 Pavia Italy

5. Dipartimento di Scienza e Alta TecnologiaUniversità degli Studi dell'Insubria Via Valleggio 11 22100 Como Italy

6. Dipartimento di ChimicaUniversità degli Studi di Pavia Viale Taramelli 12 27100 Pavia Italy

Funder

Associazione Italiana per la Ricerca sul Cancro

Publisher

Wiley

Subject

General Chemistry,Catalysis,Organic Chemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/chem.201900169

Reference86 articles.

2. Crystal Structure of the Extracellular Segment of Integrin αVβ3

3. Crystal Structure of the Extracellular Segment of Integrin αVβ3 in Complex with an Arg-Gly-Asp Ligand

4. Three-dimensional EM structure of the ectodomain of integrin αVβ3 in a complex with fibronectin

5. Complete integrin headpiece opening in eight steps

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