Development of a Concise Synthesis of (−)‐Oseltamivir (Tamiflu)

Author:

Trost Barry M.1,Zhang Ting2

Affiliation:

1. Department of Chemistry, Stanford University, Stanford, CA 94305‐5080 (USA), Fax: (+1) 650‐725‐0002

2. Department of Medicinal Chemistry, Merck Research Laboratories, PO Box 2000, RY800‐B310 Rahway, NJ 07065 (USA)

Publisher

Wiley

Subject

General Chemistry,Catalysis,Organic Chemistry

Reference117 articles.

1. For information on H5N1 avian flu and H5N1 virus visit: http://www.nature.com/avianflu/index.html. For information on H1N1 flu and H1N1 virus visit: http://www.cdc.gov/h1n1flu/.

2. For reviews on Tamiflu synthesis see:

3. Tamiflu: The Supply Problem

4. Synthetic Strategies for Oseltamivir Phosphate

5. Synthetic Approaches to the Neuraminidase Inhibitors Zanamivir (Relenza) and Oseltamivir Phosphate (Tamiflu) for the Treatment of Influenza

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