Solvent Choice and Kinetic Isotope Effects (KIEs) Dramatically Alter Regioselectivity in the DirectedorthoMetalation (DoM) of 1,5-Dichloro-2,4-dimethoxybenzene-Reference-Cited by-同舟云学术

Solvent Choice and Kinetic Isotope Effects (KIEs) Dramatically Alter Regioselectivity in the DirectedorthoMetalation (DoM) of 1,5-Dichloro-2,4-dimethoxybenzene

Published:2014-12-02 Issue:5 Volume:21 Page:1888-1893
ISSN:0947-6539
Container-title:Chemistry - A European Journal
language:en
Short-container-title:Chem. Eur. J.

Author:

Farmer Jennifer L.,Froese Robert D. J.,Lee-Ruff Edward,Organ Michael G.

Publisher

Wiley

Subject

General Chemistry,Catalysis,Organic Chemistry

Reference47 articles.

1. Relative Reactivities of Organometallic Compounds. XX.* Metalation

2. Über das Verhalten der halogenierten Anisole gegen Phenyl‐lithium (V. Mitteil. über die Reaktionsweise des Phenyl‐lithiums)

3. Directed lithiation of aromatic tertiary amides: an evolving synthetic methodology for polysubstituted aromatics

4. Directed ortho metalation. Tertiary amide and O-carbamate directors in synthetic strategies for polysubstituted aromatics

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