Modulation of Antimalarial Activity at a Putative Bisquinoline Receptor In Vivo Using Fluorinated Bisquinolines

Author:

Fielding Alistair J.1ORCID,Lukinović Valentina1ORCID,Evans Philip G.2,Alizadeh-Shekalgourabi Said3,Bisby Roger H.4ORCID,Drew Michael G. B.5,Male Verity5,Del Casino Alessio6,Dunn James F.6,Randle Laura E.6,Dempster Nicola M.6,Nahar Lutfun6,Sarker Satyajit D.6,Cantú Reinhard Fabián G.7ORCID,de Visser Sam P.7ORCID,Dascombe Mike J.8,Ismail Fyaz M. D.6ORCID

Affiliation:

1. School of Chemistry and the Photon Science Institute; The University of Manchester; Manchester M13 9PL UK

2. Peakdale Molecular Limited; Discovery Park, Sandwich Kent CT13 9FF UK

3. Department of Pharmacy; University of Hertfordshire, Hatfield; Hertfordshire AL10 9AB UK

4. Biomedical Sciences Research Institute; University of Salford; Salford M5 4WT UK

5. School of Chemistry; The University of Reading, Whiteknights; Reading RG6 6AD UK

6. Medicinal Chemistry and Natural Products Research Group; School of Pharmacy and Biomolecular Sciences; Liverpool John Moores University; Byrom Street Liverpool L3 3AF UK

7. Manchester Institute of Biotechnology; School of Chemical Engineering and Analytical Science; The University of Manchester; 131 Princess Street Manchester M1 7DN UK

8. Faculty of Biology, Medicine and Health, Stopford Building 1.124; The University of Manchester; Oxford Road Manchester M13 9PT UK

Funder

Seventh Framework Programme

Publisher

Wiley

Subject

General Chemistry,Catalysis,Organic Chemistry

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