Neutrophil Elastase Promotes Linker Cleavage and Paclitaxel Release from an Integrin-Targeted Conjugate-Reference-Cited by-同舟云学术

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Neutrophil Elastase Promotes Linker Cleavage and Paclitaxel Release from an Integrin-Targeted Conjugate

Published:2018-12-27 Issue:7 Volume:25 Page:1696-1700
ISSN:0947-6539
Container-title:Chemistry - A European Journal
language:en
Short-container-title:Chem. Eur. J.

Author:

Raposo Moreira Dias André¹^ORCID,Pina Arianna¹^ORCID,Dean Amelia¹,Lerchen Hans-Georg²^ORCID,Caruso Michele³,Gasparri Fabio³,Fraietta Ivan³,Troiani Sonia³,Arosio Daniela⁴^ORCID,Belvisi Laura¹⁴^ORCID,Pignataro Luca¹^ORCID,Dal Corso Alberto¹^ORCID,Gennari Cesare¹⁴^ORCID

Affiliation:

1. Università degli Studi di Milano; Dipartimento di Chimica; Via C. Golgi, 19 I-20133 Milan Italy

2. Medicinal Chemistry Wuppertal, Bayer AG; 42113 Wuppertal Germany

3. Nerviano Medical Sciences; Viale Pasteur, 10 I-20014 Nerviano Italy

4. CNR, Istituto di Scienze e Tecnologie Molecolari (ISTM); Via C. Golgi, 19 I-20133 Milan Italy

Funder

Ministero dell’Istruzione, dell’Università e della Ricerca

European Commission

Università degli Studi di Milano

Erasmus+

Publisher

Wiley

Subject

General Chemistry,Catalysis,Organic Chemistry

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/chem.201805447/fullpdf

Reference77 articles.

1. Antibody-Drug Conjugates: An Emerging Concept in Cancer Therapy

2. Antikörper-Wirkstoff-Konjugate: ein neues Konzept in der Krebstherapie

3. Strategies and challenges for the next generation of antibody–drug conjugates

4. Current Trends in the Clinical Development of Antibody-Drug Conjugates in Oncology

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4. Discovery of VIP236, an αvβ3-Targeted Small-Molecule–Drug Conjugate with Neutrophil Elastase-Mediated Activation of 7-Ethyl Camptothecin Payload for Treatment of Solid Tumors;Cancers;2023-09-01

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