Molecular Recognition at the Active Site of Catechol‐ O ‐methyltransferase (COMT): Adenine Replacements in Bisubstrate Inhibitors-Reference-Cited by-同舟云学术

Molecular Recognition at the Active Site of Catechol‐ O ‐methyltransferase (COMT): Adenine Replacements in Bisubstrate Inhibitors

Published:2011-04-27 Issue:23 Volume:17 Page:6369-6381
ISSN:0947-6539
Container-title:Chemistry – A European Journal
language:en
Short-container-title:Chem. Eur. J.

Author:

Ellermann Manuel¹,Paulini Ralph¹,Jakob‐Roetne Roland²,Lerner Christian²,Borroni Edilio²,Roth Doris²,Ehler Andreas²,Schweizer W. Bernd¹,Schlatter Daniel²,Rudolph Markus G.²,Diederich François¹

Affiliation:

1. Laboratorium für Organische Chemie, ETH‐Zürich, Wolfgang‐Pauli‐Strasse 10, 8093 Zürich (Switzerland), Fax: (+41) 1‐632‐1109

2. Pharma Division, Präklinische Forschung, F. Hoffmann‐La Roche AG, 4070 Basel (Switzerland)

Publisher

Wiley

Subject

General Chemistry,Catalysis,Organic Chemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/chem.201003648

Reference61 articles.

1. Catechol-O-methyltransferase-Inhibiting Pyrocatechol Derivatives: Synthesis and Structure-Activity Studies

2. Entacapone

3. Tolcapone

4. Treatment of Parkinson's disease: levodopa as the first choice

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