Orthogonal 19 F-Labeling for Solid-State NMR Spectroscopy Reveals the Conformation and Orientation of Short Peptaibols in Membranes-Reference-Cited by-同舟云学术

Orthogonal 19 F-Labeling for Solid-State NMR Spectroscopy Reveals the Conformation and Orientation of Short Peptaibols in Membranes

Published:2018-02-21 Issue:17 Volume:24 Page:4328-4335
ISSN:0947-6539
Container-title:Chemistry - A European Journal
language:en
Short-container-title:Chem. Eur. J.

Author:

Grage Stephan L.¹,Kara Sezgin²^ORCID,Bordessa Andrea³,Doan Véronique³,Rizzolo Fabio³⁴,Putzu Marina⁵,Kubař Tomáš⁵^ORCID,Papini Anna Maria³⁴^ORCID,Chaume Grégory³,Brigaud Thierry³^ORCID,Afonin Sergii¹^ORCID,Ulrich Anne S.¹²^ORCID

Affiliation:

1. Institute of Biological Interfaces (IBG-2); Karlsruhe Institute of Technology (KIT); POB 3640 76021 Karlsruhe Germany

2. Institute of Organic Chemistry (IOC); KIT; Fritz-Haber Weg 6 76131 Karlsruhe Germany

3. Laboratoire de Chimie Biologique (LCB); EA4505; Platform PeptLab@UCP; Université de Cergy-Pontoise; 5 Mail Gay-Lussac Neuville sur Oise 95000 Cergy-Pontoise cedex France

4. French-Italian Interdepartmental Laboratory of Peptide and Protein Chemistry and Biology (PeptLab); Department of Chemistry “Ugo Schiff”; CNR-IBB; University of Florence; 50019 Sesto Fiorentino Italy

5. Institute of Physical Chemistry (IPC); Center for Functional Nanostructures (CFN); KIT; 76131 Karlsruhe Germany

Funder

Deutsche Forschungsgemeinschaft

Helmholtz-Gemeinschaft

Agence Nationale de la Recherche

Publisher

Wiley

Subject

General Chemistry,Catalysis,Organic Chemistry

Reference34 articles.

1. Characterization of a type of ?-bend ribbon spiral generated by the repeating (Xaa-Yaa-Aib-Pro) motif: The solution structure of harzianin HC IX, a 14-residue peptaibol forming voltage-dependent ion channels

2. 20-Residue and 11-residue peptaibols from the fungusTrichoderma longibrachiatumare synergistic in forming Na+/K+-permeable channels and adverse action towards mammalian cells