A Single Mutation is Sufficient to Modify the Metal Selectivity and Specificity of a Eukaryotic Manganese Superoxide Dismutase to Encompass Iron-Reference-Cited by-同舟云学术

A Single Mutation is Sufficient to Modify the Metal Selectivity and Specificity of a Eukaryotic Manganese Superoxide Dismutase to Encompass Iron

Published:2017-12-12 Issue:20 Volume:24 Page:5303-5308
ISSN:0947-6539
Container-title:Chemistry - A European Journal
language:en
Short-container-title:Chem. Eur. J.

Author:

Hunter Thérèse¹,Bonetta Rosalin¹,Sacco Anthony²,Vella Marita¹,Sultana Paul-Michael¹,Trinh Chi H.³,Fadia Hava B. R.³,Borowski Tomasz⁴,Garcia-Fandiño Rebeca⁵,Stockner Thomas⁶,Hunter Gary J.¹^ORCID

Affiliation:

1. Department of Physiology and Biochemistry; University of Malta; Msida MSD2080 Malta

2. Institute of Earth Systems; University of Malta; Msida MSD2080 Malta

3. Astbury Centre of Structural Molecular Biology; University of Leeds; Leeds LS29JT UK

4. Jerzy Haber Institute of Catalysis and Surface Chemistry; Polish Academy of Sciences; Krakaw Poland

5. Center for Research in Biological Chemistry and Molecular Materials; Santiago de Compostela University; Spain

6. Institute of Pharmacology; Medical University of Vienna; Waehringerstr. 13A 1090 Vienna Austria

Funder

University of Malta

Publisher

Wiley

Subject

General Chemistry,Catalysis,Organic Chemistry

Reference44 articles.

1. Metal Preferences and Metallation

2. Efficient Production of Active Human Manganese Superoxide Dismutase in Escherichia Coli

3. GroESL protects superoxide dismutase (SOD)— Deficient cells against oxidative stress and is a chaperone for SOD

4. Superoxide dismutases—a review of the metal-associated mechanistic variations

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