Detailed Investigation of the Immunodominant Role of O-Antigen Stoichiometric O-Acetylation as Revealed by Chemical Synthesis, Immunochemistry, Solution Conformation and STD-NMR Spectroscopy forShigella flexneri 3a

Author:

Boutet Julien1234,Blasco Pilar54,Guerreiro Catherine12,Thouron Françoise67,Dartevelle Sylvie89,Nato Farida89,Cañada F. Javier5,Ardá Ana510,Phalipon Armelle67,Jiménez-Barbero Jesús51011,Mulard Laurence A.12

Affiliation:

1. Institut Pasteur; Unité de Chimie des Biomolécules; 28 rue du Dr. Roux 75724 Paris Cedex 15 France

2. CNRS UMR 3523; Institut Pasteur; 75015 Paris France

3. Université Paris Descartes; Institut Pasteur; 75015 Paris France

4. Present address for J.B.: Adisseo (France), Present address for P.B.; Dept. of Organic Chemistry; Arrhenius Laboratory; Stockholm University; 10691 Stockholm Sweden

5. Chemical and Physical Biology; Centro de Investigaciones Biológicas, CSIC; Ramiro de Maeztu 9 28040 Madrid Spain

6. Institut Pasteur; Unité de Pathogénie Microbienne Moléculaire; 28 rue du Dr. Roux 75015 Paris France

7. INSERM U1202; Institut Pasteur; 75015 Paris France

8. Institut Pasteur, PF5; 28 rue du Dr. Roux 75015 Paris France

9. CNRS UMR 3528; Institut Pasteur, 75015; Paris France

10. Molecular Recognition & Host-Pathogen Interactions Program; CIC bioGUNE, Bizkaia Technological Park, Building 801A; 48160 Derio Spain

11. Ikerbasque; Basque Foundation for Science; Maria Lopez de Haro 3 48013 Bilbao Spain

Funder

Agence Nationale de la Recherche

ANR

MENRT

European Commission Seventh Framework Program

MINECO

Publisher

Wiley

Subject

General Chemistry,Catalysis,Organic Chemistry

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