Synthesis of Mono- and Bis(fluoroalkyl)pyrimidines from FARs, Fluorinated Acetoacetates, and Malononitrile Provides Easy Access to Novel High-Value Pyrimidine Scaffolds-Reference-Cited by-同舟云学术

Synthesis of Mono- and Bis(fluoroalkyl)pyrimidines from FARs, Fluorinated Acetoacetates, and Malononitrile Provides Easy Access to Novel High-Value Pyrimidine Scaffolds

Published:2017-11-23 Issue:6 Volume:24 Page:1311-1316
ISSN:0947-6539
Container-title:Chemistry - A European Journal
language:en
Short-container-title:Chem. Eur. J.

Author:

Schmitt Etienne¹²,Commare Bruno¹²,Panossian Armen¹²^ORCID,Vors Jean-Pierre³²,Pazenok Sergiy⁴²,Leroux Frédéric R.¹²^ORCID

Affiliation:

1. Laboratoire de Chimie Moléculaire; Université de Strasbourg, CNRS, UMR 7509; 25, rue Becquerel 67087 Strasbourg France

2. Joint Laboratory CNRS-Université de Strasbourg-Bayer, LCR C2OF; France

3. Bayer S.A.S.; 14, Impasse Pierre Baizet, BP99163 69263 Lyon Cedex 09 France

4. Bayer A.G.; Alfred-Nobel-Strasse 50 40789 Monheim Germany

Publisher

Wiley

Subject

General Chemistry,Catalysis,Organic Chemistry

Reference44 articles.

1. Pyrimidine as Constituent of Natural Biologically Active Compounds

2. Metal-Bearing and Trifluoromethyl-Substituted Pyrimidines: Generation and Functionalization

3. Development of Two Scalable Syntheses of 4-Amino-5-aminomethyl-2-methylpyrimidine: Key Intermediate for Vitamin B1

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