Inosine Can Increase DNA′s Susceptibility to Photo‐oxidation by a RuIIComplex due to Structural Change in the Minor Groove

Author:

Keane Páraic M.12ORCID,Hall James P.13,Poynton Fergus E.24,Poulsen Bjørn C.24,Gurung Sarah P.13,Clark Ian P.5,Sazanovich Igor V.5,Towrie Michael5,Gunnlaugsson Thorfinnur24ORCID,Quinn Susan J.6ORCID,Cardin Christine J.1ORCID,Kelly John M.2ORCID

Affiliation:

1. Department of ChemistryUniversity of Reading, Whiteknights Reading RG6 6AD UK

2. School of ChemistryTrinity College Dublin Dublin 2 Ireland

3. Diamond Light Source, Harwell Science and Innovation CampusDidcot Oxfordshire OX11 0DE UK

4. Trinity Biomedical Sciences Institute Pearse St. Dublin 2 Ireland

5. Central Laser FacilityResearch Complex at Harwell, STFC Rutherford Appleton LaboratoriesDidcot Oxfordshire OX11 0QX UK

6. School of ChemistryUniversity College Dublin, Belfield Dublin 4 Ireland

Funder

Biotechnology and Biological Sciences Research Council

Royal Irish Academy

Royal Society

Science Foundation Ireland

Science and Technology Facilities Council

Irish Research Council for Science, Engineering and Technology

Publisher

Wiley

Subject

General Chemistry,Catalysis,Organic Chemistry

Reference81 articles.

1. Inosine is the nucleoside of the hypoxanthine nucleobase just as guanosine is the nucleoside of guanine. However it is common to use inosine as the generic term and this has been followed in the current study.

2.  

3. Adenosine-to-inosine RNA editing shapes transcriptome diversity in primates

4. Inosine in DNA and RNA

5. Functions and Regulation of RNA Editing by ADAR Deaminases

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