On the Importance of an Acid Additive in the Synthesis of Pyrido[1,2‐ a ]benzimidazoles by Direct Copper‐Catalyzed Amination
Author:
Affiliation:
1. Organic Synthesis, University of Antwerp, Groenenborgerlaan 171, 2020 Antwerp (Belgium), Fax: (+32) 32653233
2. Cryospectroscopy, University of Antwerp, Groenenborgerlaan 171, 2020 Antwerp (Belgium)
Publisher
Wiley
Subject
General Chemistry,Catalysis,Organic Chemistry
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/chem.201100574
Reference102 articles.
1. G. Tennant The Chemistry of Heterocyclic Compounds Vol. 40 1980 Wiley‐Interscience New York 257 461
2. For routes to specifically substituted pyrido[1 2‐a]benzimidazoles see:
3. One-Step Synthesis of Pyrido[1,2-a]benzimidazole Derivatives by a Novel Multicomponent Reaction of Chloroacetonitrile, Malononitrile, Aromatic Aldehyde, and Pyridine
4. Heteroaromatic Annulation of 2-Methyl/2-Cyanomethylbenzimidazole Dianions with α-Oxoketene Dithioacetals: A Highly Regioselective Synthetic Protocol for 1,2- and 2,3-Substituted/Annulated Pyrido[1,2-a]benzimidazoles
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