Loss of Sprouty Produces a Ciliopathic Skeletal Phenotype in Mice Through Upregulation of Hedgehog Signaling-Reference-Cited by-同舟云学术

Loss of Sprouty Produces a Ciliopathic Skeletal Phenotype in Mice Through Upregulation of Hedgehog Signaling

Published:2021-09-20 Issue:11 Volume:36 Page:2258-2274
ISSN:0884-0431
Container-title:Journal of Bone and Mineral Research
language:en
Short-container-title:J Bone Miner Res

Author:

Hruba Eva¹²,Kavkova Michaela³,Dalecka Linda⁴⁵^ORCID,Macholan Miloš¹^ORCID,Zikmund Tomas³,Varecha Miroslav⁶,Bosakova Michaela¹⁶^ORCID,Kaiser Jozef³,Krejci Pavel¹⁶,Hovorakova Maria⁴^ORCID,Buchtova Marcela¹²^ORCID

Affiliation:

1. Institute of Animal Physiology and Genetics Czech Academy of Sciences Brno Czech Republic

2. Department of Experimental Biology, Faculty of Science Masaryk University Brno Czech Republic

3. Central European Institute of Technology Brno University of Technology Brno Czech Republic

4. Institute of Histology and Embryology, First Faculty of Medicine Charles University Prague Czech Republic

5. Department of Cell Biology, Faculty of Science Charles University Prague Czech Republic

6. Department of Biology, Faculty of Medicine Masaryk University Brno Czech Republic

Funder

Central European Institute of Technology

Grantová Agentura České Republiky

Ministerstvo Školství, Mládeže a Tělovýchovy

Publisher

Wiley

Subject

Orthopedics and Sports Medicine,Endocrinology, Diabetes and Metabolism

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/jbmr.4427

Reference59 articles.

1. sprouty Encodes a Novel Antagonist of FGF Signaling that Patterns Apical Branching of the Drosophila Airways

2. Cloning and expression pattern of a mouse homologue of Drosophila sprouty in the mouse embryo

3. Vertebrate Sprouty genes are induced by FGF signaling and can cause chondrodysplasia when overexpressed

4. Expression of sprouty2 during early development of the chick embryo is coincident with known sites of FGF signalling

5. Expression of Sprouty genes 1 , 2 and 4 during mouse organogenesis

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