QT Interval Shortening With Isavuconazole: In Vitro and In Vivo Effects on Cardiac Repolarization-Reference-Cited by-同舟云学术

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QT Interval Shortening With Isavuconazole: In Vitro and In Vivo Effects on Cardiac Repolarization

Published:2017-02-13 Issue:6 Volume:101 Page:782-790
ISSN:0009-9236
Container-title:Clinical Pharmacology & Therapeutics
language:en
Short-container-title:Clin. Pharmacol. Ther.

Author:

Keirns J¹,Desai A¹,Kowalski D¹,Lademacher C¹,Mujais S¹,Parker B¹,Schneidkraut MJ¹,Townsend R¹,Wojtkowski T¹,Yamazaki T¹,Yen M²,Kowey PR³⁴

Affiliation:

1. Astellas Pharma Global Development, Inc; Northbrook Illinois USA

2. PAREXEL; Glendale California USA

3. Lankenau Medical Center and Institute for Medical Research, Main Line Health System; Wynnewood Pennsylvania USA

4. Jefferson Medical College; Philadelphia Pennsylvania USA

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Reference31 articles.

1. Drug-induced long QT syndrome;Kannankeril;Pharmacol. Rev.,2010

2. Antimicrobial-associated QT interval prolongation: pointes of interest;Owens;Clin. Infect. Dis.,2006

3. Voriconazole-induced QT interval prolongation and ventricular tachycardia: a non-concentration-dependent adverse effect;Alkan;Clin. Infect. Dis.,2004

4. Prolonged QT interval and torsades de pointes caused by the combination of fluconazole and amitriptyline;Dorsey;Am. J. Emerg. Med.,2000

5. Blockade of HERG and Kv1.5 by ketoconazole;Dumaine;J. Pharmacol. Exp. Ther.,1998

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