Frequent PTEN loss and differential HER2/PI3K signaling pathway alterations in salivary duct carcinoma: Implications for targeted therapy

Author:

Saintigny Pierre123,Mitani Yoshitsugu4ORCID,Pytynia Kristen B.5,Ferrarotto Renata6ORCID,Roberts Dianna B.5,Weber Randal S.5,Kies Merrill S.6,Maity Sankar N.7,Lin Sue-Hwa8,El-Naggar Adel K.4

Affiliation:

1. Univ Lyon, Université Claude Bernard Lyon 1, INSERM 1052, CNRS 5286, Centre Léon Bérard, Centre de Recherche en Cancérologie de Lyon; Lyon France

2. Department of Translational Research and Innovation; Centre Léon Bérard; Lyon France

3. Department of Medical Oncology; Centre Léon Bérard; Lyon France

4. Department of Pathology; The University of Texas MD Anderson Cancer Center; Houston Texas

5. Department of Head and Neck Surgery; The University of Texas MD Anderson Cancer Center; Houston Texas

6. Department of Thoracic/Head and Neck Medical Oncology; The University of Texas MD Anderson Cancer Center; Houston Texas

7. Department of Genitourinary Medical Oncology; The University of Texas MD Anderson Cancer Center; Houston Texas

8. Department of Translational Molecular Pathology; The University of Texas MD Anderson Cancer Center; Houston Texas

Funder

National Institute of Dental and Craniofacial Research

National Institutes of Health

NIH Office of Rare Diseases Research

Salivary Gland Tumor Cell Biorepository

Head and Neck Specialized Programs of Research Excellence (SPORE)

National Cancer Institute

Publisher

Wiley

Subject

Cancer Research,Oncology

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