Structures and dynamics of DNA complexes of the desmethyl analog of the cytotoxin MLN944: Insights into activity when a methyl isn't futile-Reference-Cited by-同舟云学术

Structures and dynamics of DNA complexes of the desmethyl analog of the cytotoxin MLN944: Insights into activity when a methyl isn't futile

Published:2020-04-06 Issue:8 Volume:33 Page:
ISSN:0952-3499
Container-title:Journal of Molecular Recognition
language:en
Short-container-title:J Mol Recognit

Author:

Serobian Andre¹,Pracey Christopher P.²,Thomas Donald S.³,Denny William A.⁴,Ball Graham E.²^ORCID,Wakelin Laurence P. G.¹

Affiliation:

1. Department of Pharmacology, School of Medical Sciences, Faculty of MedicineUNSW Sydney Sydney New South Wales Australia

2. School of Chemistry, Faculty of ScienceUNSW Sydney Sydney New South Wales Australia

3. NMR Facility, Mark Wainwright Analytical CentreUNSW Sydney Sydney New South Wales Australia

4. Auckland Cancer Society Research Centre, School of Medical Sciences, Faculty of Health and Medical SciencesUniversity of Auckland Auckland New Zealand

Publisher

Wiley

Subject

Molecular Biology,Structural Biology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/jmr.2843

Reference54 articles.

1. Potential antitumor agents. 44. Synthesis and antitumor activity of new classes of diacridines: importance of linker chain rigidity for DNA binding kinetics and biological activity

2. Potential antitumor agents. 49. 5-Substituted derivatives of N-[2-(dimethylamino)ethyl]-9-aminoacridine-4-carboxamide with in vivo solid-tumor activity

3. Potential antitumor agents. 36. Quantitative relationships between experimental antitumor activity, toxicity, and structure for the general class of 9-anilinoacridine antitumor agents

4. Potential antitumor agents. 59. Structure-activity relationships for 2-phenylbenzimidazole-4-carboxamides, a new class of minimal DNA-intercalating agents which may not act via topoisomerase II

5. Interrelations between anti‐tumour activity, DNA breakage, and DNA binding kinetics for 9‐aminoacridinecarboxamide anti‐tumour agents;Denny WA;Anticancer Drug Des,1986

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