Clearance of porcine circovirus and porcine parvovirus from porcine‐derived pepsin by low pH inactivation and cation exchange chromatography

Author:

Yang Bin1ORCID,Wang Hua1,Kaleas Kimberly1,Butler Michelle1,Franklin Jayme1,Bill Amber1,Baylis Sally A.2,Chen Qi1,Blümel Johannes2

Affiliation:

1. Purification DevelopmentGenentech, Inc., One DNA Way South San Francisco California

2. Virus Safety SectionPaul‐Ehrlich‐Institut, Federal Institute for Vaccines and Biomedicines Langen Germany

Publisher

Wiley

Subject

Biotechnology

Reference31 articles.

1. EMA.2010a. European Medicines Agency sees no safety concerns with the Rotarix oral vaccine. London UK: European Medicines Agency. Doc. Ref. EMA/CHMP/201923/2010.

2. EMA2010b. European Medicines Agency confirms positive benefit‐risk balance of Rotarix. London UK: European Medicines Agency. Doc. Ref. EMA/CHMP/462029/2010.

3. Viral Nucleic Acids in Live-Attenuated Vaccines: Detection of Minority Variants and an Adventitious Virus

4. Molecular and infectivity studies of porcine circovirus in vaccines

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