Holistic process development to mitigate proteolysis of a subunit rotavirus vaccine candidate produced in Pichia pastoris by means of an acid pH pulse during fed‐batch fermentation
Author:
Affiliation:
1. Department of Biochemical EngineeringUniversity College London London United Kingdom
2. Department of Pharmaceutical Chemistry, Vaccine Analytics and Formulation CenterUniversity of Kansas Lawrence Kansas
Funder
Bill and Melinda Gates Foundation
Publisher
Wiley
Subject
Biotechnology
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/btpr.2966
Reference31 articles.
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3. Global, Regional, and National Estimates of Rotavirus Mortality in Children <5 Years of Age, 2000–2013
4. The rotavirus vaccine development pipeline
5. Effect of Human Rotavirus Vaccine on Severe Diarrhea in African Infants
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