Pharmacodynamic and genomic markers associated with response to the XPO1/CRM1 inhibitor selinexor (KPT-330): A report from the pediatric preclinical testing program

Author:

Attiyeh Edward F.,Maris John M.1,Lock Richard2,Reynolds C. Patrick3,Kang Min H.3,Carol Hernan2,Gorlick Richard4,Kolb E. Anders5,Keir Stephen T.6,Wu Jianrong7,Landesman Yosef8,Shacham Sharon8,Lyalin Dmitry9,Kurmasheva Raushan T.9,Houghton Peter J.9,Smith Malcolm A.10

Affiliation:

1. Children's Hospital of Philadelphia; University of Pennsylvania School of Medicine and Abramson Family Cancer Research Institute; Philadelphia Pennsylvania

2. Children's Cancer Institute Australia for Medical Research; Randwick New South Wales Australia

3. Texas Tech University Health Sciences Center; Lubbock Texas

4. The Children's Hospital at Montefiore; Bronx New York

5. A.I. duPont Hospital for Children; Wilmington Delaware

6. Duke University Medical Center; Durham North Carolina

7. St. Jude Children's Research Hospital; Memphis Tennessee

8. Karyopharm Therapeutics; Newton Massachusetts

9. Nationwide Children's Hospital; Columbus Ohio

10. Cancer Therapy Evaluation Program, NCI; Bethesda Maryland

Funder

National Cancer Institute

Publisher

Wiley

Subject

Oncology,Hematology,Pediatrics, Perinatology and Child Health

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