Analytical characterization of broadly neutralizing antibody <scp>CAP256LS</scp> heavy chain clipping during manufacturing development-Reference-Cited by-同舟云学术

Analytical characterization of broadly neutralizing antibody CAP256LS heavy chain clipping during manufacturing development

Published:2022-08-29 Issue:6 Volume:38 Page:
ISSN:8756-7938
Container-title:Biotechnology Progress
language:en
Short-container-title:Biotechnology Progress

Author:

Gollapudi Deepika¹,Rosales‐Zavala Erwin¹,Ivleva Vera B.¹,Yang Yanhong¹,Li Yile¹,O'Connell Sarah¹,Doria‐Rose Nicole A.¹,Patel Aakash¹,Blackstock Daniel¹,Gowetski Daniel B.¹,Carlton Kevin¹,Gall Jason G. D.¹,Lei Q. Paula¹^ORCID

Affiliation:

1. Vaccine Production Program, VRC, NIAID, NIH Gaithersburg Maryland USA

Funder

National Institutes of Health

National Institute of Allergy and Infectious Diseases

Publisher

Wiley

Subject

Biotechnology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/btpr.3296

Reference21 articles.

1. Global HIV & AIDS statistics — 2020 fact sheet.www.unaids.org. Accessed November 13 2020.

2. Structure and immune recognition of trimeric pre-fusion HIV-1 Env

3. Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B, and G

4. Structure of Super-Potent Antibody CAP256-VRC26.25 in Complex with HIV-1 Envelope Reveals a Combined Mode of Trimer-Apex Recognition

5. New Member of the V1V2-Directed CAP256-VRC26 Lineage That Shows Increased Breadth and Exceptional Potency

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1. Application of Formulation Principles to Stability Issues Encountered During Processing, Manufacturing, and Storage of Drug Substance and Drug Product Protein Therapeutics;Journal of Pharmaceutical Sciences;2023-11

2. Engineering of HIV-1 neutralizing antibody CAP256V2LS for manufacturability and improved half life;Scientific Reports;2022-10-25