Integrative clinical transcriptome analysis reveals TMPRSS2‐ERG dependency of prognostic biomarkers in prostate adenocarcinoma

Author:

Gerke Julia S.1,Orth Martin F.1,Tolkach Yuri2,Romero‐Pérez Laura1,Wehweck Fabienne S.1,Stein Stefanie1,Musa Julian1,Knott Maximilian M.L.13,Hölting Tilman L.B.1,Li Jing1,Sannino Giuseppina1,Marchetto Aruna1,Ohmura Shunya1,Cidre‐Aranaz Florencia1,Müller‐Nurasyid Martina456,Strauch Konstantin7,Stief Christian8,Kristiansen Glen2,Kirchner Thomas3910,Buchner Alexander6,Grünewald Thomas G.P.13910ORCID

Affiliation:

1. Max‐Eder Research Group for Pediatric Sarcoma BiologyInstitute of Pathology, Faculty of Medicine, LMU Munich Munich Germany

2. Institute of Pathology, University Hospital Bonn Bonn Germany

3. Institute of Pathology, Faculty of Medicine, LMU Munich Munich Germany

4. Institute of Genetic Epidemiology, Helmholtz Zentrum München – German Research Center for Environmental Health Neuherberg Germany

5. Chair of Genetic Epidemiology, IBE, Faculty of Medicine, LMU Munich Munich Germany

6. Department of Internal Medicine I (Cardiology)Hospital of the LMU Munich Munich Germany

7. Institute of Medical Biostatistics, Epidemiology and Informatics (IMBEI), University Medical Center, Johannes Gutenberg University Mainz Germany

8. Urologic Clinic und PolyclinicClinical Center of the University of Munich Munich Germany

9. German Cancer Consortium (DKTK), partner site Munich Munich Germany

10. German Cancer Research Center (DKFZ) Heidelberg Germany

Funder

Deutsche Forschungsgemeinschaft

Deutsche Krebshilfe

Wilhelm Sander-Stiftung

Friedrich-Baur-Stiftung

Publisher

Wiley

Subject

Cancer Research,Oncology

Reference42 articles.

1. Landmarks in prostate cancer

2. Cancer Research UK. Cancer Research UK prostate cancer.2018. Available from:http://www.cancerresearchuk.org/health-professional/cancer-statistics/statistics-by-cancer-type/prostate-cancer/survival#heading-Four. Accessed January 14 2018.

3. Effect of Treatment on Quality of Life Among Men With Clinically Localized Prostate Cancer

4. Prostate cancer genomics: can we distinguish between indolent and fatal disease using genetic markers? Genome medicine;Wiklund F;BioMed Central,2010

5. Global Cancer Incidence and Mortality Rates and Trends—An Update

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