Computational characterisation of the interactions between human ST6Gal I and transition-state analogue inhibitors: insights for inhibitor design
Author:
Affiliation:
1. School of Chemistry, Faculty of Science, Medicine and Health; University of Wollongong; Wollongong NSW 2522 Australia
2. Centre for Medical and Molecular Bioscience; University of Wollongong; Wollongong NSW 2522 Australia
Funder
Australian Research Council
Publisher
Wiley
Subject
Molecular Biology,Structural Biology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/jmr.2520/fullpdf
Reference57 articles.
1. New potent sialyltransferase inhibitors-synthesis of donor and of transition-state analogues of sialyl donor CMP-Neu5Ac;Amann;Chem. Eur. J.,1998
2. Rattle: a “velocity” version of the shake algorithm for molecular dynamics calculations;Andersen;J. Comput. Phys.,1983
3. Current trends in the structure-activity relationships of sialyltransferases;Audry;Glycobiology,2011
4. Recent structures, evolution and mechanisms of glycosyltransferases;Breton;Curr. Opin. Struct. Biol.,2012
5. CHARMM: the biomolecular simulation program;Brooks;J. Comput. Chem.,2009
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