Platinum‐based chemotherapy plus cetuximab first‐line for Asian patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck: Results of an open‐label, single‐arm, multicenter trial

Author:

Guo Ye1,Shi Mei2,Yang Ankui3,Feng Jifeng4,Zhu Xiaodong5,Choi Young‐Jin6,Hu Guoqin7,Pan Jianji8,Hu Chunhong9,Luo Rongcheng10,Zhang Yiping11,Zhou Liang12,Cheng Ying13,Lüpfert Christian14,Cai Junliang15,Shi yuankai16

Affiliation:

1. Medical Oncology DepartmentFudan University Shanghai Cancer CenterShanghai China

2. Radiation Oncology DepartmentXijing Hospital – The First Affiliated Hospital of the Fourth Military Medical University Shanxi Province China

3. Head and Neck DepartmentSun Yat‐sen University Cancer CenterGuangzhou China

4. Medical Oncology DepartmentJiangsu Cancer HospitalNanjing Jiangsu Province China

5. Radiotherapy DepartmentAffiliated Cancer Hospital, Guangxi Medical UniversityNanning Guangxi Province China

6. Medical Oncology DepartmentPusan National University HospitalSeo‐Gu Busan Korea

7. Cancer DepartmentTongji Hospital of Tongji Medical College of Huazhong University of Science and TechnologyWuhan China

8. Department of Radiation OncologyFujian Provincial Cancer HospitalFuzhou China

9. Oncology DepartmentThe Second Xiangya Hospital of Central South UniversityChangsha Hu'nan Province China

10. Cancer Medical DepartmentNanfang HospitalGuangzhou China

11. Chemotherapy CenterZhejiang Cancer HospitalHangzhou Zhejiang Province China

12. Head and Neck Surgery DepartmentEye and Ear, Nose, and Throat Hospital of Fudan UniversityXuhui District Shanghai China

13. Medical Oncology DepartmentJilin Cancer HospitalChangchun Jilin China

14. Merck KGaADarmstadt Germany

15. Merck Serono (Beijing) Pharmaceutical R&D CompanyThe Center Shanghai China

16. Department of Medical OncologyCancer Institute/Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing Key Laboratory of Clinical Study on Anticancer Molecular Targeted DrugsChaoyang District Beijing China

Funder

The trial was sponsored by Merck KGaA, Darmstadt, Germany

Publisher

Wiley

Subject

Otorhinolaryngology

Reference25 articles.

1. Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008

2. Chinese Cancer Registry Annual Report 2008: National Office for Cancer Prevention and Control and National Central Cancer Registry Disease Prevention and Control Bureau Ministry of Health;2009.

3. Optimal treatment for recurrent/metastatic head and neck cancer

4. NCCN Clinical Practice Guidelines in Oncology: Head and Neck Cancers. Version 1.2012 ed.National Comprehensive Cancer Network Inc.;2012. Available at:http://www.nccn.org. Accessed August 1 2013.

5. Squamous cell carcinoma of the head and neck: EHNS–ESMO–ESTRO Clinical Practice Guidelines for diagnosis, treatment and follow-up

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