Ang II-AT1R Increases Cell Migration Through PI3K/AKT and NF-κB Pathways in Breast Cancer

Author:

Zhao Yanbin1,Wang Hongbin2,Li Xiuli1,Cao Mengru1,Lu Hailing1,Meng Qingwei1,Pang Hui1,Li Hailin3,Nadolny Christina4,Dong Xiaoqun4,Cai Li1

Affiliation:

1. Department of Internal Medical Oncology; Harbin Medical University Cancer Hospital; Harbin Heilongjiang Province China

2. Department of Surgical Oncology; Harbin Medical University Cancer Hospital; Harbin Heilongjiang Province China

3. Hongqi Hospital; Mudanjiang Heilongjiang Province China

4. Department of Biomedical and Pharmaceutical Sciences; College of Pharmacy, The University of Rhode Island; Kingston Rhode Island

Funder

Educational Commission of Heilongjiang Province of China

Publisher

Wiley

Subject

Cell Biology,Clinical Biochemistry,Physiology

Reference45 articles.

1. AT1 receptors activation enhances the expression of MMP-2, MMP-13 and VEGF but not MMP-9 in B16F10 melanoma cells;Akhavan;Pak J Biol Sci,2011

2. Angiotensin II activates MAP kinase and NF-kappaB through angiotensin II type I receptor in human pancreatic cancer cells;Amaya;Int J Oncol,2004

3. Expression of AT1 and AT2 angiotensin receptors in astrocytomas is associated with poor prognosis;Arrieta;Br J Cancer,2008

4. Integrin beta1 upregulation in MCF-7 breast cancer cells by angiotensin II;Berry;Eur J Surg Oncol,2000

5. The phosphatidyl inositol 3-kinase/AKT signaling pathway in breast cancer;Castaneda;Cancer Metastasis Rev,2010

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