Pharmacokinetic-pharmacodynamic modeling of fostamatinib efficacy on ACR20 to support dose selection in patients with rheumatoid arthritis (RA)
Author:
Affiliation:
1. Quantitative Solutions BV; Breda The Netherlands
2. AstraZeneca Quantitative Clinical Pharmacology; Södertälje/Mölndal Sweden
3. Quantitative Clinical Pharmacology; Alderley Park UK
Publisher
Wiley
Subject
Pharmacology (medical),Pharmacology
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3. Treatment of rheumatoid arthritis with a Syk kinase inhibitor: a twelve-week, randomized, placebo-controlled trial;Weinblatt;Arthritis Rheum,2008
4. An oral syk kinase inhibitor in the treatment of rheumatoid arthritis: a 3 month randomized placebo controlled phase 2 study in patients with active RA who had failed biologic agents;Genovese;Arthritis Rheum,2011
5. Continuous time Markov models for binary longitudinal data;Jones;Biometric J,2006
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