Development ofKrasmutant lung adenocarcinoma in mice with knockout of the airway lineage-specific geneGprc5a

Author:

Fujimoto Junya1,Nunomura-Nakamura Sayuri12,Liu Yihua3,Lang Wenhua1,McDowell Tina1,Jakubek Yasminka3,Ezzeddine Dalia4,Kapere Ochieng Joshua1,Petersen Jason5,Davies Gareth5,Fukuoka Junya2,Wistuba Ignacio I.1,Ehli Erik5,Fowler Jerry3,Scheet Paul3,Kadara Humam16ORCID

Affiliation:

1. Department of Translational Molecular Pathology; The University of Texas MD Anderson Cancer Center; Houston TX

2. Graduate School of Biomedical Science; Nagasaki University; Nagasaki Japan

3. Department of Epidemiology; The University of Texas MD Anderson Cancer Center; Houston TX

4. Department of Chemistry; American University of Beirut; Beirut Lebanon

5. Avera Institute for Human Genetics; Sioux Falls SD

6. Department of Biochemistry and Molecular Genetics, Faculty of Medicine; American University of Beirut; Beirut Lebanon

Funder

University Cancer Foundation via the Institutional Research Grant program at MD Anderson Cancer Center

Lung Cancer Discovery Award from the American Lung Association

National Cancer Institute

NCI Cancer Center

Medical Research Volunteer Program (MRVP) at the American University of Beirut

Publisher

Wiley

Subject

Cancer Research,Oncology

Reference53 articles.

1. Cancer statistics, 2017;Siegel;Cancer J Clin,2017

2. Global cancer incidence and mortality rates and trends-an update;Torre;Cancer Epidemiol Biomarkers Prevent,2016

3. Lung cancer;Herbst;N Engl J Med,2008

4. Early events in the molecular pathogenesis of lung cancer;Kadara;Cancer Prev Res (Phila),2016

5. Effects of cigarette smoke on the human airway epithelial cell transcriptome;Spira;Proc Natl Acad Sci USA,2004

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