Separation and characterization of unknown impurities in cefonicid sodium by trap-free two-dimensional liquid chromatography combined with ion trap time-of-flight mass spectrometry
Author:
Affiliation:
1. Zhejiang University of Technology; Hangzhou 310014 China
2. Zhejiang Institute for Food and Drug Control; Hangzhou 310052 China
Funder
The Food and Drug Science and Technology project of Zhejiang Food and Drug Administration in 2016
Publisher
Wiley
Subject
Organic Chemistry,Spectroscopy,Analytical Chemistry
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/rcm.7934/fullpdf
Reference23 articles.
1. Synthesis of cefonicid sodium;Zhang;Chin J Pharm,2009
2. An improvement for synthesis of cefonicid sodium;Wei;Chin J New Drugs,2012
3. Identification of degradation compound of cephalosporins by LC/MS;Hu;Chin J Pharm Anal,2005
4. Analysis of β-lactam antibiotics by high performance liquid chromatography/atmospheric pressure chemical ionization mass spectrometry using bromoform;Horimoto;J Pharm Biomed Anal,2002
5. High-resolution LC/MS for analysis of minor components in complex mixtures: Negative ion ESI for identification of impurities and degradation products of a novel oligosaccharide antibiotic;Shipkova;J Mass Spectrom,2000
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