Affiliation:
1. Department of Head and Neck Surgery & Communication Sciences Duke University School of Medicine Durham North Carolina U.S.A.
2. Duke Center for the Study of Aging and Human Development Durham North Carolina U.S.A.
3. Duke Medical Center Library Duke University School of Medicine Durham North Carolina U.S.A.
Abstract
ObjectiveDespite its relatively high prevalence, our understanding of the natural clinical course of acute low‐tone hearing loss (ALHL) without vertigo remains incomplete. The purpose of this study is to summarize the findings of studies that evaluated recovery from hearing loss (HL), recurrence and/or fluctuation of HL, and progression to Meniere's Disease (MD) of patients presenting with ALHL without vertigo.MethodsA scoping review of the English literature was performed. On May 14, 2020 and July 6, 2022, MEDLINE, Embase, and Scopus were searched to identify articles related to the prognosis of ALHL. To be included, articles had to present outcomes that were clearly distinguishable for patients with ALHL without vertigo. Two reviewers evaluated articles for inclusion and extracted data. Disagreements were adjudicated by a third reviewer.ResultsForty‐one studies were included. There was extensive heterogeneity between studies in regard to defining ALHL, treatment methods, and time of follow‐up. Most of the cohorts (39 out of 40) reported partial or complete recovery of hearing in the majority (>50%) of patients, although reports of recurrence were relatively common. Progression to MD was infrequently reported. Shorter time from onset of symptoms to treatment predicted better hearing outcomes in 6 of 8 studies.ConclusionThe literature suggests that although the majority of patients with ALHL experience hearing improvement, recurrence and/or fluctuation are common, and progression to MD occurs in a minority of patients. Additional trials utilizing standardized inclusion and outcome criteria are needed to determine the ideal treatment for ALHL.Level of EvidenceNA Laryngoscope, 133:2457–2469, 2023
Funder
National Institute on Deafness and Other Communication Disorders