Variants in Pharmacokinetic Transporters and Glycemic Response to Metformin: A Metgen Meta-Analysis

Author:

Dujic T12,Zhou K2,Yee SW3,van Leeuwen N4,de Keyser CE56,Javorský M78,Goswami S3,Zaharenko L9,Hougaard Christensen MM10,Out M1112,Tavendale R2,Kubo M13,Hedderson MM14,van der Heijden AA15,Klimčáková L16,Pirags V9,Kooy A1112,Brøsen K17,Klovins J9,Semiz S118,Tkáč I78,Stricker BH5619,Palmer CNA2,'t Hart LM42021,Giacomini KM322,Pearson ER2

Affiliation:

1. Department of Biochemistry and Clinical Analysis; Faculty of Pharmacy, University of Sarajevo; Sarajevo Bosnia and Herzegovina

2. Division of Molecular and Clinical Medicine; School of Medicine, University of Dundee; Dundee UK

3. Department of Bioengineering and Therapeutic Sciences; University of California, San Francisco; San Francisco California USA

4. Department of Molecular Cell Biology; Leiden University Medical Center; Leiden The Netherlands

5. Department of Epidemiology; Erasmus Medical Center; Rotterdam The Netherlands

6. Inspectorate of Healthcare; Utrecht The Netherlands

7. Department of Internal Medicine 4; Faculty of Medicine, Šafárik University; Košice Slovakia

8. Pasteur University Hospital; Košice Slovakia

9. Latvian Biomedical Research and Study Centre; Riga Latvia

10. Department of Clinical Chemistry and Pharmacology; Odense University Hospital; Odense Denmark

11. Treant Zorggroep; Location Bethesda Hoogeveen The Netherlands

12. Bethesda Diabetes Research Centre; Hoogeveen The Netherlands

13. Core for Genomic Medicine; RIKEN Center for Integrative Medical Sciences; Yokohama Japan

14. Division of Research; Kaiser Permanente Northern California; Oakland California USA

15. Department of General Practice; EMGO+ Institute for Health and Care Research, VU University Medical Center; Amsterdam The Netherlands

16. Department of Medical Biology; Faculty of Medicine, Šafárik University; Košice Slovakia

17. Department of Public Health; Clinical Pharmacology and Pharmacy, University of Southern Denmark; Odense Denmark

18. International University of Sarajevo; Faculty of Engineering and Natural Sciences; Sarajevo Bosnia and Herzegovina

19. Department of Internal Medicine; Erasmus Medical Center; Rotterdam The Netherlands

20. Department of Molecular Epidemiology; Leiden University Medical Center; Leiden The Netherlands

21. Department of Epidemiology and Biostatistics; EMGO+ Institute for Health and Care Research, VU University Medical Center; Amsterdam The Netherlands

22. Institute for Human Genetics; University of California, San Francisco; San Francisco California USA

Funder

Diabetes Care System West-Friesland

ZonMw

Innovative Medicines Initiative Joint Undertaking

European Union's Seventh Framework Programme

EFPIA

Wellcome Trust

Ministry of Education, Science, Research and Sport

National Institutes of Health

RIKEN Institute

GERA

Robert Wood Johnson Foundation

Ellison Medical Foundation

Wayne and Gladys Valley Foundation

Kaiser Permanente

Council of Ministers/Ministry of Civil Affairs of Bosnia and Herzegovina

Federal Ministry for Education and Science of Bosnia and Herzegovina

AJ Andersen and Wife's Foundation

AP Moeller Foundation for the Advancement of Medical Science

Region of Southern Denmark

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

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