TBDLNet: A network for classifying multidrug‐resistant and drug‐sensitive tuberculosis

Author:

Zhu Ziquan1,Tao Jing2,Wang Shuihua13,Zhang Xin2,Zhang Yudong145ORCID

Affiliation:

1. School of Computing and Mathematical Sciences University of Leicester East Midlands UK

2. Medical Imaging Department of Huai'an Fourth People's Hospital Huai'an China

3. Department of Biological Sciences Xi'an Jiaotong‐Liverpool University, Suzhou Jiangsu China

4. School of Computer Science and Technology Henan Polytechnic University, Jiaozuo Henan People's Republic of China

5. Department of Information Systems Faculty of Computing and Information Technology, King Abdulaziz University Jeddah Saudi Arabia

Abstract

AbstractThis paper proposes applying a novel deep‐learning model, TBDLNet, to recognize CT images to classify multidrug‐resistant and drug‐sensitive tuberculosis automatically. The pre‐trained ResNet50 is selected to extract features. Three randomized neural networks are used to alleviate the overfitting problem. The ensemble of three RNNs is applied to boost the robustness via majority voting. The proposed model is evaluated by five‐fold cross‐validation. Five indexes are selected in this paper, which are accuracy, sensitivity, precision, F1‐score, and specificity. The TBDLNet achieves 0.9822 accuracy, 0.9815 specificity, 0.9823 precision, 0.9829 sensitivity, and 0.9826 F1‐score, respectively. The TBDLNet is suitable for classifying multidrug‐resistant tuberculosis and drug‐sensitive tuberculosis. It can detect multidrug‐resistant pulmonary tuberculosis as early as possible, which helps to adjust the treatment plan in time and improve the treatment effect.

Funder

Biotechnology and Biological Sciences Research Council

British Heart Foundation

Fight for Sight UK

GCRF

MRC

Royal Society

Publisher

Wiley

Subject

General Engineering,General Computer Science

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