Assessment of a Nonsteroidal Aromatase Inhibitor, Letrozole, in Juvenile Rats

Author:

Pouliot Louise1,Schneider Marilynn2,DeCristofaro Marc2,Samadfam Rana1,Smith Susan Y.1,Beckman David A.2

Affiliation:

1. Charles River Preclinical Services; Senneville QC Canada

2. Preclinical Safety; Novartis Institutes for BioMedical Research; East Hanover New Jersey

Publisher

Wiley

Subject

Health, Toxicology and Mutagenesis,Developmental Biology,Toxicology,Embryology

Reference28 articles.

1. Peripubertal aromatase inhibition in male rats has adverse long-term effects on bone strength and growth and induces prostatic hyperplasia;Bajpai;J Endocrinol,2010

2. Age- and cell-related gene expression of aromatase and estrogen receptors in the rat testis;Bois;J Mol Endocrinol,2010

3. Impaired reproduction in adult male but not female, rats following juvenile treatment with the aromatase inhibitor, exemestrane;Cappon;Birth Defects Res Pt B,2011

4. Oestrogens and spermatogenesis;Carreau;Phil Trans R Soc B,2010

5. Aromatase, oestrogens and human male reproduction;Carreau;Phil Trans R Soc B,2010

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