Intratumoral temozolomide in spontaneous canine gliomas: feasibility of a novel therapy using implanted microcylinders

Author:

Hicks Jill1ORCID,Platt Simon1,Stewart Georgina1,Senneca Christine2,Holmes Shannon1,Kent Marc1,Howerth Elizabeth1,Kaplan Jared3,Kaplan Edward4

Affiliation:

1. Veterinary Teaching Hospital; University of Georgia; Athens Georgia USA

2. Small Animal Hospital; University of Florida; Gainesville FL USA

3. Department of Internal Medicine; Yale Medical School; New Haven CT USA

4. Microspherix LLC; Bocan Raton FL USA

Funder

Microspherix LLC

Publisher

Wiley

Subject

General Veterinary

Reference38 articles.

1. Development of microspheres for neurological disorders: from basics to clinical applications;Benoit;Journal of Controlled Release,2000

2. Canine intracranial gliomas: relationship between magnetic resonance imaging criteria and tumor type and grade;Bentley;The Veterinary Journal,2013

3. Local delivery of temozolomide by biodegradable polymers is superior to oral administration in a rodent glioma model;Brem;Cancer Chemotherapy Pharmacology,2007

4. Comparative magnetic resonance imaging findings between gliomas and presumed cerebrovascular accidents in dogs;Cervera;Veterinary Radiology & Ultrasound,2011

5. Sustained release of ganciclovir from poly(lactide-co-glycolide) microspheres;Chen;Journal of Microencapsulation,2005

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