Affiliation:
1. Department of Neurosurgery Yagi Neurosurgical Hospital Higashinariku Osaka Japan
2. Department of Neurosurgery Nara Medical University Kashihara Nara Japan
3. Department of Neurosurgery Osaka Medical and Pharmaceutical University Takatsuki Osaka Japan
Abstract
AbstractObjectiveEndovascular therapy (EVT) is performed for acute ischemic stroke (AIS) with large vessel occlusion (LVO), however, the treatment strategies and clinical outcomes differ between cardiac embolism (CE) and intracranial arteriosclerosis‐derived LVO (ICAS‐LVO). We analyzed whether the time‐to‐max (Tmax) volume derived from perfusion imaging predicted clinical classification in AIS patients before EVT.MethodsConsecutive AIS patients with anterior circulation LVO evaluated by automated imaging software were retrospectively identified. Patients were classified into a CE group and an ICAS‐LVO group, and parameters were compared between groups.ResultsThirty‐nine patients were included and Tmax volume and Tmax > 6 s volume/Tmax > 4 s volume were significantly greater in the CE group than in the ICAS‐LVO group (Tmax > 4 s volume: 261 mL vs. 149 mL, p = .01, Tmax > 6 s volume: 143 mL vs. 59 mL, p = .001, Tmax > 6 s volume/Tmax > 4 s volume: 0.59 vs. 0.40, p < .001). Multiple logistic regression analysis indicated an association between clinical classification and high Tmax > 6 s volume/Tmax > 4 s volume (p = .04).ConclusionThe Tmax volume derived from perfusion imaging predicts the clinical classification of AIS patients before EVT.
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